Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Yoshiyuki Takahashi"'
Autor:
Franco Locatelli, Hyoung Jin Kang, Bénédicte Bruno, Virginie Gandemer, Fanny Rialland, Maura Faraci, Yoshiyuki Takahashi, Katsuyoshi Koh, Henrique Bittencourt, Grace Cleary, Christine Rosko, Pantelia Roussou, Annie St. Pierre, Anirudh Prahallad, Cristina Díaz-de-Heredia
Publikováno v:
Blood. 140:1376-1378
Autor:
Yoshiyuki Takahashi, Nobuhiro Nishio, Hideki Muramatsu, Rieko Taniguchi, Yuichi Ishikawa, Makoto Murata, Nozomu Kawashima, Eri Nishikawa, Ryo Hanajiri, Motoharu Hamada, Atsushi Narita
Publikováno v:
Blood. 138:3831-3831
Introduction: Chimeric antigen receptor-modified T cells targeting CD19 (CD19.CAR-T cells) have shown clinical success in patients with hematological malignancies. Despite the encouraging results obtained with this novel therapy, a major concern to i
Autor:
Masayuki Imaya, Tomoo Ogi, Yoshiyuki Takahashi, Manabu Wakamatsu, Eri Nishikawa, Masafumi Ito, Hideki Muramatsu, Kotaro Narita, Daisuke Ichikawa, Seiji Kojima, Atsushi Narita, Rieko Taniguchi, Nobuhiro Nishio, Yusuke Okuno, Shunsuke Miwata, Taro Yoshida, Motoharu Hamada, Asahito Hama, Nozomu Kawashima, Ayako Yamamori
Publikováno v:
Blood. 136:9-9
BACKGROUND: Inherited bone marrow failure syndromes (IBMFSs) are a heterogeneous group of genetic disorders characterized by bone marrow failure, physical anomalies, and various kinds of organ complications. In addition to classical IBMFSs, such as F
Autor:
Haichan Xu, Biljana Horn, Rui Zhang, Sanfang Tu, Le-Ping Zhang, Cheng Jiao, Yu-Chen Liu, Yuan Sun, Yuhua Li, Yoshiyuki Takahashi, Zhouyang Liu, Bin Wang, Jia Feng, Yuchen Li, Lung-Ji Chang, Xue Song, Yi-Fei Cheng, Yongping Zhang, Huyong Zheng, Juan Xiao, Kai Wang, Nobuhiro Nishio
Publikováno v:
Blood. 136:7-7
BACKGROUND: Allogeneic haematopoietic stem cell transplantation (allo-HCT) is a standard treatment for relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL). However ~30-40% of patients (pts) still relapse after HCT. We report a cohort
Autor:
Yoshiyuki Takahashi, Seiji Kojima, Manabu Wakamatsu, Norihiro Murakami, Hironobu Kitazawa, Yusuke Okuno, Hideki Muramatsu
Publikováno v:
Blood. 134:4213-4213
Background Juvenile myelomonocytic leukemia (JMML) is a rare pediatric myelodysplastic/myeloproliferative disease. Approximately 85% of patients with JMML harbor germline and/or somatic mutations in RAS pathway genes, such as PTPN11, NF1, CBL, NRAS,
Autor:
Yusuke Okuno, Norihiro Murakami, Yoshiyuki Takahashi, Tomoo Ogi, Manabu Wakamatsu, Hideki Muramatsu, Nozomu Kawashima, Hironobu Kitazawa
Publikováno v:
Blood. 134:2974-2974
Background Juvenile myelomonocytic leukemia (JMML) is a rare and exclusively pediatric myelodysplastic/myeloproliferative neoplasm. This disease is genetically characterized by an extremely small number of somatic mutations (an average of 0.8 mutatio
Autor:
Elliot Stieglitz, Manabu Wakamatsu, Mark Hartmann, Yusuke Okuno, Mignon L. Loh, Hideki Muramatsu, Maximillian Schönung, Adam B. Olshen, Julia Meyer, Daniel B. Lipka, Norihiro Murakami, Christian Flotho, Christoph Plass, Yoshiyuki Takahashi, Charlotte M. Niemeyer
Publikováno v:
Blood. 134:1693-1693
Introduction: Juvenile myelomonocytic leukemia is a heterogenous disease of early childhood that has both myelodysplastic and myeloproliferative properties. Outcomes range from spontaneous resolution with little to no therapy in some patients while o
Autor:
Yusuke Okuno, Seiji Kojima, Eri Nishikawa, Nobuhiro Nishio, Hirohito Yamazaki, Shinji Nakao, Yinyan Xu, Hideki Muramatsu, Atsushi Narita, Motoharu Hamada, Nozomu Kawashima, Daisuke Ichikawa, Yoshiyuki Takahashi
Publikováno v:
Blood. 134:2505-2505
Introduction: Aplastic anemia (AA) is an autoimmune-mediated disease with a complex mechanism. Innate as well as acquired immune system have been considered to participate in its pathogenesis. Although several studies have demonstrated the role of T
Autor:
Yusuke Okuno, Hideki Muramatsu, Masayuki Imaya, Rieko Taniguchi, Ayako Yamamori, Motoharu Hamada, Taro Yoshida, Manabu Wakamatsu, Nozomu Kawashima, Eri Nishikawa, Seiji Kojima, Yoshiyuki Takahashi, Daisuke Ichikawa, Nobuhiro Nishio, Kotaro Narita, Hironobu Kitazawa, Shunsuke Miwata, Norihiro Murakami, Atsushi Narita
Publikováno v:
Blood. 134:2973-2973
Background Juvenile myelomonocytic leukemia (JMML) is a rare myelodysplastic/ myeloproliferative neoplasm that occurs during infancy and early childhood. The clinical course of the disease varies widely. The majority of children require allogenic hem
Autor:
Ikuya Tsuge, Hideki Muramatsu, Seiji Kojima, Yusuke Okuno, Yoshiyuki Takahashi, Sakai Yoshimi, Manabu Wakamatsu, Yoko Nakajima, Tetsuya Ito, Shinsuke Kataoka
Publikováno v:
Blood. 134:3604-3604
Background Severe combined immune deficiency (SCID) is a potentially fatal primary immunodeficiency due to the absence of T and B lymphocyte function. Early intervention for patients with SCID results in a higher survival rate. From 2017, we launched