Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Steven Jacobson"'
Autor:
Jing Chen, Steven Jacobson, Meili Zhang, Wei Ju, Jian Kang Jiang, John C. Morris, Yutaka Tagaya, Thomas A. Waldmann, Noriko Sato, John E. Janik, Bonita R. Bryant, Craig J. Thomas, Unsong Oh
Publikováno v:
Blood. 117:1938-1946
The retrovirus, human T-cell–lymphotrophic virus-1 (HTLV-I) is the etiologic agent of adult T-cell leukemia (ATL) and the neurological disorder HTLV-I–associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-I–encoded protein tax
Autor:
Francesco M. Marincola, Y. Yamano, Kina Smith, Stephen A. Migueles, Vladia Monsurrò, Steven Jacobson, Monica C. Panelli, Mark Connors, Ena Wang, Dirk Nagorsen
Publikováno v:
Blood. 104:1970-1978
In a human melanoma model of tumor antigen (TA)–based immunization, we tested the functional status of TA-specific CD8+ cytotoxic T lymphocytes. A “quiescent” phenotype lacking direct ex vivo cytotoxic and proliferative potential was identified
Publikováno v:
Blood. 98:1858-1861
It is thought that human T-cell lymphotropic virus type I (HTLV-I) preferentially infects CD4+ T cells in vivo. However, observations of high HTLV-I proviral load in patients with HTLV-I–associated myelopathy/tropical spastic paraparesis suggest th
Publikováno v:
Blood. 98:1506-1511
Peripheral blood mononuclear cells (PBMCs) from patients with human T-cell lymphotropic virus type I (HTLV-I)–associated myelopathy/tropical spastic paraparesis (HAM/TSP) proliferate spontaneously in vitro. This spontaneous lymphoproliferation (SP)
Autor:
M Migita, Stefan Karlsson, Steven Jacobson, R Pawliuk, Jeffrey A. Medin, R K Humphries, Stefanie Kluepfel-Stahl, M Amiri, Roscoe O. Brady
Publikováno v:
Blood. 87:1754-1762
Corrective gene transfer for therapeutic intervention in metabolic and hematopoietic disorders has been hampered by the relatively inefficient transduction of human hematopoietic stem cells. To overcome this, a bicistronic recombinant retrovirus has
Publikováno v:
Blood. 119(12)
Adult T-cell leukemia (ATL) and human T-cell lymphotropic virus type I (HTLV-I)–associated myelopathy/tropical spastic paraparesis (HAM/TSP) are known to be caused by HTLV-I infection. However, current methods used to determine HTLV-I infection do
Publikováno v:
Blood. 111(12)
We previously demonstrated that CD4+CD25+ T regulatory cells (Tregs), important for the maintenance of immune tolerance and prevention of autoimmune disease, from patients with human T lymphotropic virus type I (HTLV-I)–associated myelopathy/tropic
Autor:
Meghan B. Brennan, Steven Jacobson, Mitsuhiro Osame, Carlos A. Mora, Norihiro Takenouchi, Samantha S. Soldan, Shuji Izumo, Masahiro Nagai, Yoshihisa Yamano, Utano Tomaru
Publikováno v:
Blood. 99(1)
To investigate the role of viral expression in individuals infected with human T-cell lymphotropic virus type 1 (HTLV-1), a real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) of HTLV-1 tax messenger RNA (mRNA) using ABI P
Autor:
Steven Jacobson, Tanya Lehky, Robert J. Fox, Marc Krichavsky, Michael C. Levin, R. Jeffrey Edwards, Noreen E. Jack, Courtenay Bartholomew
Publikováno v:
Blood. 89:346-347