Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Cathy S. Wang"'
Autor:
Brian Zahab, Haiming Chen, Nicole Ng, Sean Bujarski, Cathy S Wang, Edward J Tanenbaum, George Tang, Ning Xu, Jasmin Cao, Tara Hekmati, Eric Sanchez, James R. Berenson, Mingjie Li, Camilia Soof
Publikováno v:
Blood. 132:1910-1910
Introduction: Ruxolitinib (RUX) is an inhibitor of the Janus kinase family of protein tyrosine kinases (JAKs) that is effective for the treatment of myeloproliferative diseases. Immunomodulatory drugs including lenalidomide (LEN) and corticosteroids
Autor:
Saurabh Patil, Eric Sanchez, James R. Berenson, Camilia Soof, Regina A. Swift, Kian J. Rahbari, Haiming Chen, Marsiye Emamy-Sadr, Sean Bujarski, Cathy S Wang, Tanya M. Spektor, Mingjie Li
Publikováno v:
Blood. 132:1894-1894
Background: B-cell maturation antigen (BCMA) is highly expressed on malignant plasma cells from patients with multiple myeloma (MM). We have previously shown that serum (s) BCMA levels are elevated among MM patients, and baseline levels predict both
Autor:
George Tang, Cathy S Wang, Mingjie Li, Eric Sanchez, James R. Berenson, Haiming Chen, Puja K. Mehta
Publikováno v:
Blood. 128:3297-3297
Introduction: Several studies have demonstrated constitutive activation of the JAK-STAT pathway in MM through dysregulated signaling of cytokines such as IL-6. In addition to its crucial role in promoting the growth, proliferation and survival of mye
Autor:
Kyle Udd, Zachary Gross, Eric Sanchez, Mingjie Li, James R. Berenson, Soudabeh Etessami, James Wang, Matthew Ghermezi, Cathy S Wang, Camilia Soof, Haiming Chen, Regina A. Swift, Marsiye Emamy-Sadr, Christian E. Casas
Publikováno v:
Blood. 128:5654-5654
Introduction: B-cell maturation antigen (BCMA) is a protein found on the surface of malignant plasma cells from multiple myeloma (MM) patients (pts). We have previously shown that MM pts show higher serum (s) levels of BCMA than healthy subjects and
Autor:
Tanya M. Spektor, Mingjie Li, Kyle Udd, Cathy S Wang, Zachary Gross, Camilia Soof, George Tang, Eric Sanchez, James R. Berenson, Matthew Ghermezi, Soudabeh Etessami, Regina A. Swift, Christian E. Casas, Haiming Chen
Publikováno v:
Blood. 128:5652-5652
Introduction: CD147 is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily. CD147 gene expression levels are elevated in several types of human cancer. Recent studies show that expression of CD147 is increased in multiple myel
Autor:
Kyle Udd, George Tang, Christian E. Casas, Cathy S Wang, Kevin DeCorso, Jessica Wang, Mingjie Li, Jasmin Cao, Tara Hekmati, Eric Sanchez, James R. Berenson, Camilia Soof, Haiming Chen
Publikováno v:
Blood. 128:5641-5641
Introduction: B-cell maturation antigen (BCMA) has been shown to be highly expressed on the surface of tumor cells from patients (pts) with multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) and is the target for therapeutic approaches in t
Autor:
Steven J. Manyak, Thomas F. Deuel, Benjamin Bonavida, Melinda S. Gordon, Dorina Gui, Haiming Chen, Yunchao Chang, Stavroula Baritaki, Richard A. Campbell, Hee Jin Lee, Dror Shalitin, Eric Sanchez, James R. Berenson, Cathy S. Wang, Jonathan W. Said, Mingjie Li
Publikováno v:
Blood. 110(1)
Pleiotrophin (PTN) is an important developmental cytokine that is highly expressed during embryogenesis but shows very limited expression in adult tissues, where it is largely restricted to the brain. High PTN serum levels are associated with a varie
Autor:
Cathy S Wang, Eric Sanchez, James R. Berenson, Mingjie Li, Kevin Delijani, Mitchell Song, Ran Halleluyan, Joseph Ben-Zvi, Haiming Chen, Jillian Gottlieb, Suzie Vardanyan
Publikováno v:
Blood. 122:4452-4452
Introduction We previously demonstrated that severe combined immunodeficient (SCID) mice bearing the human multiple myeloma (MM) xenograft LAGκ-1A treated with single agent carfilzomib or the alkylating agent (AA) cyclophosphamide (CY) did not show
Autor:
Haiming Chen, Benjamin Bonavida, Cathy S Wang, Kevin DeCorso, Jennifer S. Li, Danielle Rauch, Eric Sanchez, James R. Berenson, Andrew Prajogi, Kevin Delijani, Mingjie Li
Publikováno v:
Blood. 120:4986-4986
Abstract 4986 Background: Janus kinase 2 (JAK2) is a cytoplasmic tyrosine kinase that carries out a series of cascading signals via signal transducer and activator of transcription (STAT)s, mitogen-activated protein kinase (MAPK), and phosphorylation
Autor:
Haiming Chen, Eric Sanchez, James R. Berenson, Cathy S Wang, Jennifer Li, Danielle Rauch, Mingjie Li, Kevin DeCorso, Kevin Delijani, Andrew Prajogi, Alex Kitto
Publikováno v:
Blood. 120:4026-4026
Abstract 4026 Background: B cell maturation antigen (BCMA) is a receptor whose expression increases during B-cell development and is found on malignant cells from multiple myeloma (MM) patients; however, it has not been identified in human serum. Met