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pro vyhledávání: '"Baglin, A."'
Autor:
Ty E. Adams, Stéphanie G. I. Polderdijk, Trevor Baglin, Rodney M. Camire, Lacramioara Ivanciu, James A. Huntington
Publikováno v:
Blood. 129:105-113
Hemophilia is a bleeding disorder caused by deficiency in factors VIII or IX, the two components of the intrinsic Xase complex. Treatment with replacement factor can lead to the development of inhibitory antibodies, requiring the use of bypassing age
Akademický článek
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Publikováno v:
Blood. 124(12)
In this study, we describe a novel thrombomodulin (TM) mutation (c.1611C>A) that codes for a change from cysteine 537 to a premature stop codon (p.Cys537Stop). Three members of a family with a history of posttraumatic bleeding were identified to be h
Publikováno v:
Blood. 91:508-515
The importance of lipoproteins in the etiology of atherosclerosis is well established. Evidence is now accumulating to implicate thrombin in the pathogenesis of atherosclerosis. We have investigated whether atherogenic lipoproteins can support thromb
Publikováno v:
Blood. 104:1718-1718
Heparin cofactor II(HCII) is a serpin which specifically inhibits thrombin. Like antithrombin(AT) it requires glycosaminoglycan(GAG) binding before full activation. However unlike antithrombin no specific activators have been identified. What current