Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Scarpa A"'
Autor:
Sandrine Niyongere, Shivani Kapoor, Jonelle K. Lee, Danilo Perrotti, Mario Scarpa, Prerna Singh, Maria R. Baer, Goutham Narla
Publikováno v:
Blood. 134:1276-1276
Introduction fms-like tyrosine like kinase 3 internal tandem duplication (FLT3-ITD), present in acute myeloid leukemia (AML) cells of 30% of patients, results in constitutive and aberrant FLT3 signaling and, clinically, short disease-free survival. E
Publikováno v:
Blood. 132:3951-3951
Introduction: In 30% of acute myeloid leukemia (AML) patients, internal tandem duplication of fms-like tyrosine kinase 3 (FLT3-ITD) causes constitutive and aberrant FLT3 signaling, and these patients have short relapse-free and overall survival. FLT3
Autor:
Wendy Cozen, James R. Cerhan, Tongzhang Zheng, Andrew Jack, Martha S. Linet, Jennifer Turner, Patrick A. Treseler, Lindsay M. Morton, Aldo Scarpa, Marc Maynadié, John J. Spinelli, Christina A. Clarke, Dennis D. Weisenburger, Thomas Rüdiger, Adele Seniori Costantini
Publikováno v:
Blood. 110:695-708
Recent evidence suggests that there is etiologic heterogeneity among the various subtypes of lymphoid neoplasms. However, epidemiologic analyses by disease subtype have proven challenging due to the numerous clinical and pathologic schemes used to cl
Autor:
John W. Chamberlain, Minoru Tanaka, Bernard G. Forget, Alphonse L. Scarpa, Rita Sarkar, Joelle Starck, Marc Romana, Sherman M. Weissman, Ajay K. Bhargava
Publikováno v:
Blood. 84:1656-1665
Two lines of transgenic mice carrying a normal 40-kb Kpn I beta-globin cluster transgene lacking the locus control region (LCR) were analyzed for the expression of human gamma- and beta-globin genes during mouse development. After RNase protection as
Autor:
Paola Capelli, Setsuo Hirohashi, Marco Chilosi, Luciano Fiore-Donati, Giuseppe Zamboni, Franco Bonetti, Aldo Scarpa, L. Borgato, Fabio Menestrina, Giovanni Pizzolo
Publikováno v:
Blood. 78:780-788
Six cases of mediastinal large B-cell lymphoma (MLCL) with sclerosis were analyzed for the presence and patterns of c-myc and bcl-2 loci rearrangements, and for the presence of Epstein-Barr virus DNA sequences by Southern blot hybridization, c-myc ge
Autor:
Glauco Frizzera, C de Wolf-Peeters, Shigeo Mori, A Scarpa, F Menestrina, M Chilosi, M Goldstein, A Merson, Giorgio Inghirami, S Pittaluga, Herman Yee, M Shiota, M Ponzoni
Publikováno v:
Scopus-Elsevier
The precise cellular origin and the pathogenetic mechanism(s) leading to the neoplastic transformation of anaplastic large cell lymphoma (ALCL) and the Reed-Sternberg cell of Hodgkin's disease (HD) remains largely uncertain. Classical cytogenetic ana
Autor:
Gianpaolo Nadali, Marco Chilosi, Serena Pedron, Aldo Scarpa, Ettore Macrì, Mauro Krampera, Alice Benedetti, Maria Scardoni, Giorgio Inghirami, Daoud Rahal, Fabio Menestrina, Giovanni Pizzolo, Alba Rosa Magalini, Claudio Doglioni, Maurizio Lestani
Publikováno v:
Scopus-Elsevier
p21WAF1 (wild-type p53-activated fragment 1) is involved in the control of mammalian cell cycle through the binding and inhibition of cyclin-dependent kinases (Cdk). Because the product of WAF1 gene is a potent downstream effector of the p53 tumor-su
Autor:
Yves Beuzard, C. Leboeuf, Aldo Scarpa, Anne Janin, Orah S. Platt, Alida Filippini, Lucia De Franceschi, Giorgio Malpeli
Publikováno v:
Blood. 112:1444-1444
Ischemic/reperfusion (I/R) injury plays a critical role in the pathogenesis of several clinical manifestations of sickle cell disease (SCD) and it results from complex interactions between cells and plasma factors. Hepatic dysfunction has been descri
Autor:
Emmanuel Payen, Anne Janin, Christhophe Leboeuf, Carlo Brugnara, Orah S. Platt, Yves Beuzard, Giorgio Malpeli, Lucia De Franceschi, Aldo Scarpa, Philippe Leboulch
Publikováno v:
Blood. 104:3577-3577
Pulmonary hypertension (PH) is one of the major causes of morbidity and mortality for young-adult patients with sickle cell disease (SCD). Little is known about the role of vaso-active agents, pro-inflammatory and pro-fibrotic mediators in the genesi
Autor:
Carlo Brugnara, C. Leboeuf, Philippe Leboulch, Giorgio Malpeli, Anne Janin, Yves Beuzard, Eva M. Muchitsch, Aldo Scarpa, Lucia De Franceschi
Publikováno v:
Blood. 104:3580-3580
Clinical manifestations of sickle cell disease are related to vaso-occlusive (VOC) events, which are responsible for acute and chronic organ damages. We have recently shown the beneficial effects of inhaled nitric oxide (NO) in both transgenic sickle