Zobrazeno 1 - 10
of 21
pro vyhledávání: '"785"'
Publikováno v:
Blood. 120:3789-3789
Abstract 3789 Introduction: Recently, genes affecting the splicing machinery have been found to be frequently mutated in MDS patients. The U2AF1 gene codes for one of these splicing components, showing two distinct mutational hot spots at amino acids
Publikováno v:
Blood. 132:4849-4849
Background: Newly diagnosed acute myeloid leukemia (ND AML) patients (pts) ineligible for intensive chemotherapy have limited treatment options. Most commonly used low intensity regimens are azacitidine (AZA), decitabine (DEC), or low-dose cytarabine
Autor:
Anja Mottok, Christian Steidl, Randy D. Gascoyne, Maryse M. Power, David Scott, Fong Chun Chan, Alina S. Gerrie, Kerry J. Savage, Sohrab P. Shah, Joseph M. Connors
Publikováno v:
Blood. 124:136-136
Introduction : Classical Hodgkin lymphoma (cHL) is the most common lymphoma affecting individuals under the age of 30. Despite improvements in standard treatment, 25-30% of patients still relapse after first-line treatment with ABVD. Relapsed patient
Autor:
Colin Burke O'Leary, Megha Shalavadi, Timothy S. Oh, Aryeh Pelcovits, Frederick Lansigan, Jason Lofters, Adam J. Olszewski, Reem Karmali, Elaine Kuhn, Jean L. Koff, Andrew M. Evens, Neil Palmisiano, Melissa Kives, Mingen Liu, Ning C. Dong, Andrea Anampa-Guzman, Tatyana Feldman, Nadia Khan, Stefan K. Barta, Alexey V. Danilov, Jordan Carter, Kerry J. Savage, Shazia Nakohda, Colin Thomas, Carman Tong, Francisco J. Hernandez-Ilizaliturri, Kittika Poonsombudlert, Sabarish Ayyappan, Alexander Hershey, Matthew A. Lunning
Publikováno v:
Blood. 138:50-50
Introduction: While an association between AI diseases and the development of lymphoma (LYM) is known, the impact of AI diseases on patient (pt) outcome across varying LYM subtypes, including the role of immunosuppressive medications (ISM), is not we
Autor:
Oliver Meier, Martynas Aizenas, Francis Nissen, Paul McLaughlin, Cédric Hermans, Thomas W. Burke, Harpal Dhillon, Jamie O'Hara, Sohaib Asghar
Publikováno v:
Blood. 136:33-34
Introduction Severe hemophilia A (SHA) is characterized by spontaneous (non-trauma related) bleeding episodes into the joint space and muscle tissue, leading to progressive joint deterioration and chronic pain. Chronic joint damage is most often asso
Publikováno v:
Blood. 136:21-22
Introduction Chimeric Antigen Receptor (CAR) T cell therapy has improved outcomes for relapsed and/or refractory (r/r) B cell lymphomas. Bridging therapy might be needed in some patients for disease control while CAR T product is being produced. Radi
Autor:
Harsh Vardhan Upreti, Shruti Chaturvedi, Elizabeth E. Davis, Radhika Gangaraju, Rahil Kohli, Meera Sridharan, Darla K. Liles, Frank Akwaa, Gustaaf de Ridder, Andrew D. Johnson, Spero R. Cataland, Ming Y. Lim, Angela Liu, X. Long Zheng, Kristin Bagby, Ana G Antun, Jay S. Raval, Nicole K. Kocher, Keith R. McCrae, J. Evan Sadler, Yara A. Park, Andrew M. Farland, Ara Metjian, Marshall A. Mazepa, Briana Gibson, Lisa Baumann Kreuziger, Susan Eubanks, Ronald S. Go, Raj S. Kasthuri, Ryan R Woods
Publikováno v:
Blood. 134:1066-1066
Background: Immune thrombotic thrombocytopenic purpura (iTTP) is a potentially fatal hematologic disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ischemic organ impairment. The incidence of iTTP is higher among Afric
Autor:
Natia Esiashvili, Pamela B. Allen, Mohammad K. Khan, Mary Jo Lechowicz, Christopher R. Flowers, Matthew R Kudelka
Publikováno v:
Blood. 132:1639-1639
Introduction: Total skin electron beam (TSEB) therapy is a well-established treatment modality for patients suffering from cutaneous T-cell lymphoma (CTCL). It is often augmented with maintenance therapy, including skin directed and systemic therapie
Publikováno v:
Blood. 101:822-826
Fanconi anemia (FA) is an autosomal recessive condition associated with congenital abnormalities, progressive pancytopenia, and a predisposition to leukemia and solid tumors. We studied a retrospective cohort of North American patients with FA. We ca
Autor:
C H Pui, J. L. Frestedt, David R. Head, J. H. Kersey, James R. Downing, Frederick G. Behm, Susana C. Raimondi
Publikováno v:
Blood. 86:1881-1886
Balanced translocations affecting the 11q23 region are among the most frequent chromosomal abnormalities in childhood acute lymphoblastic leukemia (ALL), comprising 5% to 6%. These cases consistently have a rearranged MLL gene and are associated with