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pro vyhledávání: '"785"'
Publikováno v:
Blood. 101:822-826
Fanconi anemia (FA) is an autosomal recessive condition associated with congenital abnormalities, progressive pancytopenia, and a predisposition to leukemia and solid tumors. We studied a retrospective cohort of North American patients with FA. We ca
Autor:
C H Pui, J. L. Frestedt, David R. Head, J. H. Kersey, James R. Downing, Frederick G. Behm, Susana C. Raimondi
Publikováno v:
Blood. 86:1881-1886
Balanced translocations affecting the 11q23 region are among the most frequent chromosomal abnormalities in childhood acute lymphoblastic leukemia (ALL), comprising 5% to 6%. These cases consistently have a rearranged MLL gene and are associated with
Autor:
Jürgen Krauter, Mark Ringhoffer, Arnold Ganser, Brigitte Schlegelberger, Daniela Späth, Marie von Lilienfeld-Toal, David Nachbaur, Hartmut Döhner, Veronica Teleanu, Gerhard Held, Michael Lübbert, Hans Martin, Verena I. Gaidzik, Gudrun Göhring, Sabine Kayser, Patricia Erdmann, Wolfgang Herr, Ulrich Germing, Mathias J. Rummel, Helmut R. Salih, Claus-Henning Köhne, Katharina Götze, H Salwender, Thomas Fischer, Richard F. Schlenk, Peter Paschka, Heinz A. Horst, Konstanze Döhner
Publikováno v:
Blood. 120:785-785
Abstract 785 Background: FLT3 internal tandem duplications (FLT3-ITD) occur in about 25% of acute myeloid leukemia (AML), are associated with cooperating gene mutations (NPM1, DNMT3A), and confer an adverse prognosis. Several studies have indicated t
Autor:
David Marin, Letizia Foroni, Richard E. Clark, Stephen J. O'Brien, Jane F. Apperley, Dragana Milojkovic, John M. Goldman, Corinne Hedgley, Christopher Pocock
Publikováno v:
Blood. 118:785-785
Abstract 785 We assessed the correlation between molecular response at 3 and 6 months of dasatinib 100mg daily treatment and subsequent cytogenetic and molecular responses in 150 newly-diagnosed chronic phase CML patients treated with front line dasa