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Autor:
Raimondi SC; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN 38105, USA., Frestedt JL, Pui CH, Downing JR, Head DR, Kersey JH, Behm FG
Publikováno v:
Blood [Blood] 1995 Sep 01; Vol. 86 (5), pp. 1881-6.
Publikováno v:
Blood. 86(5)
Balanced translocations affecting the 11q23 region are among the most frequent chromosomal abnormalities in childhood acute lymphoblastic leukemia (ALL), comprising 5% to 6%. These cases consistently have a rearranged MLL gene and are associated with