Zobrazeno 1 - 10
of 35
pro vyhledávání: '"11"'
Autor:
Zuzana Zemanova, Christine Perot, Anna Leszl, Brian V. Balgobind, Akira Morimoto, Anne Auvrignon, Todd A. Alonzo, H. Berna Beverloo, Luca Lo Nigro, Jochen Harbott, Marry M. van den Heuvel-Eibrink, Erik Forestier, Jeffrey E. Rubnitz, C. Michel Zwaan, Irina Stasevich, Franklin O. Smith, Gertjan J.L. Kaspers, Martin Zimmermann, Nathalia Litvinko, Jan Stary, Ursula Creutzig, Christine J. Harrison, Sabine Strehl, Brenda Gibson, Susana C. Raimondi, Dirk Reinhardt, Takashi Taga, David Webb, Myron Chang, Henrik Hasle, Rob Pieters, Daisuke Tomizawa, Michael Dworzak, Nyla A. Heerema
Publikováno v:
Blood, 114(12), 2489-2496. American Society of Hematology
Balgobind, B V, Raimondi, S C, Harbott, J, Zimmermann, M, Alonzo, T A, Auvrignon, A, Beverloo, HB, Chang, M, Creutzig, U, Dworzak, M, Forestier, E, Gibson, B E, Hasle, H, Harrison, C, Heerema, N A, Kaspers, G J L, Leszl, A, Litvinko, N, Lo Nigro, L, Morimoto, A, Perot, C, Pieters, R, Reinhardt, D, Rubnitz, J E, Smith, F J, Stary, J, Stasevich, I, Strehl, S, Taga, T, Tomizawa, D, Webb, D F, Zemanova, Z, Zwaan, C M & van den Heuvel-Eibrink, M 2009, ' Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study ', Blood, vol. 114, no. 12, pp. 2489-2496 . https://doi.org/10.1182/blood-2009-04-215152
Balgobind, BV, Raimondi, SC, Harbott, J, Zimmermann, M, Alonzo, TA, Auvrignon, A, Beverloo, HB, Chang, M, Creutzig, U, Dworzak, MN, Forestier, E, Gibson, B, Hasle, H, Harrison, CJ, Heerema, NA, Kaspers, GJL, Leszl, A, Litvinko, N, Nigro, LL, Morimoto, A, Perot, C, Pieters, R, Reinhardt, D, Rubnitz, JE, Smith, FO, Stary, J, Stasevich, I, Strehl, S, Taga, T, Tomizawa, D, Webb, D, Zemanova, Z, Zwaan, CM & van den Heuvel-Eibrink, MM 2009, ' Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study ', Blood, vol. 114, no. 12, pp. 2489-96 . https://doi.org/10.1182/blood-2009-04-215152
Balgobind, B V, Raimondi, S C, Harbott, J, Zimmermann, M, Alonzo, T A, Auvrignon, A, Beverloo, HB, Chang, M, Creutzig, U, Dworzak, M, Forestier, E, Gibson, B E, Hasle, H, Harrison, C, Heerema, N A, Kaspers, G J L, Leszl, A, Litvinko, N, Lo Nigro, L, Morimoto, A, Perot, C, Pieters, R, Reinhardt, D, Rubnitz, J E, Smith, F J, Stary, J, Stasevich, I, Strehl, S, Taga, T, Tomizawa, D, Webb, D F, Zemanova, Z, Zwaan, C M & van den Heuvel-Eibrink, M 2009, ' Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study ', Blood, vol. 114, no. 12, pp. 2489-2496 . https://doi.org/10.1182/blood-2009-04-215152
Balgobind, BV, Raimondi, SC, Harbott, J, Zimmermann, M, Alonzo, TA, Auvrignon, A, Beverloo, HB, Chang, M, Creutzig, U, Dworzak, MN, Forestier, E, Gibson, B, Hasle, H, Harrison, CJ, Heerema, NA, Kaspers, GJL, Leszl, A, Litvinko, N, Nigro, LL, Morimoto, A, Perot, C, Pieters, R, Reinhardt, D, Rubnitz, JE, Smith, FO, Stary, J, Stasevich, I, Strehl, S, Taga, T, Tomizawa, D, Webb, D, Zemanova, Z, Zwaan, CM & van den Heuvel-Eibrink, MM 2009, ' Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study ', Blood, vol. 114, no. 12, pp. 2489-96 . https://doi.org/10.1182/blood-2009-04-215152
Translocations involving chromosome 11q23 frequently occur in pediatric acute myeloid leukemia (AML) and are associated with poor prognosis. In most cases, the MLL gene is involved, and more than 50 translocation partners have been described. Clinica
Autor:
C Debert, Christian Bastard, Hélène Poirel, Eric Delabesse, Olivier Bernard, Xavier Troussard, D Leboeuf, Isabelle Radford-Weiss, A Veil-Buzyn, Françoise Picard, G. Flandrin, Elisabeth Macintyre, Katrina Rack
Publikováno v:
Europe PubMed Central
To determine the incidence of MLL rearrangement in acute myeloid leukemia (AML) French-American-British (FAB) type M1 and to evaluate optimal screening strategies for the characterization of such abnormalities, we analyzed specimens from 41 patients
Publikováno v:
Blood. 105:2519-2526
Glucocorticoids are among the most effective agents used in the treatment of childhood acute lymphoblastic leukemia (ALL), and patient response to treatment is an important determinant of long-term outcome. Despite its clinical significance, the mole
Autor:
David Stokoe, Elaine Carlson, Kenneth Lieuw, Suzanne Schubbert, Mignon L. Loh, Jeannette M. Bonifas, Jason Gotlib, Peter D. Emanuel, Kevin Shannon, Melissa G. Reynolds, Shashaank Vattikuti, Michelle M. Le Beau, Connie M. Lee, Soheil Meshinchi, Nicole P. Curtiss, Jennifer W. Cheng
Publikováno v:
Blood. 103:2325-2331
The PTPN11 gene encodes SHP-2 (Src homology 2 domain-containing protein tyrosine Phosphatase), a nonreceptor tyrosine protein tyrosine phosphatase (PTPase) that relays signals from activated growth factor receptors to p21Ras (Ras) and other signaling
Autor:
Hans G. Drexler, Ralf Küppers, Monika Szczepanowski, Markus Löffler, Ilske Oschlies, Lorenz Trümper, Matthias Schlesner, Birgit Burkhardt, Alexander Claviez, Inga Vater, Jasmin Lisfeld, Markus Kreuz, Barbara Pienkowska-Grela, Michael Hummel, Carsten Schwaenen, Reiner Siebert, Maciej Rosolowski, Christian W. Kohler, Christine Damm-Welk, Christine Lefebvre, Inga Nagel, Wolfram Klapper, Robert B. Russell, Rabea Wagener, Roderick A. F. MacLeod, Swen Wessendorf, Itziar Salaverria, Elaine S. Jaffe, Patrick Adam, Grzegorz Rymkiewicz, Detlev Schindler, Rainer Spang, Idoia Martin-Guerrero, Julia Richter, René Scholtysik
Publikováno v:
Blood. 123(8)
The genetic hallmark of Burkitt lymphoma (BL) is the t(8;14)(q24;q32) and its variants leading to activation of the MYC oncogene. It is a matter of debate whether true BL without MYC translocation exists. Here, we identified 59 lymphomas concordantly
Autor:
Christine Rivat, Ronjon Chakraverty, Emma C. Morris, Alan D. Salama, Anne Galy, H. Bobby Gaspar, Karen F. Buckland, Adrian J. Thrasher, Ronnie Chee, Rita Tendeiro, Sarita Workman, Thomas A. Fox, Siobhan O. Burns, Frederick D. Bushman, Kimberly Gilmour, Frances Male, Katie Butler, Cecile Duret, Sarah Grace, Katie Snell, Fulvio Mavilio, Hazem Ibrahim, Havinder Hara
Publikováno v:
Blood
Blood, 2017, 130 (11), pp.1327-1335. ⟨10.1182/blood-2017-04-777136⟩
Blood, American Society of Hematology, 2017, 130 (11), pp.1327-1335. ⟨10.1182/blood-2017-04-777136⟩
Blood, 2017, 130 (11), pp.1327-1335. ⟨10.1182/blood-2017-04-777136⟩
Blood, American Society of Hematology, 2017, 130 (11), pp.1327-1335. ⟨10.1182/blood-2017-04-777136⟩
International audience; Until recently, hematopoietic stem cell transplantation was the only curative option for Wiskott-Aldrich syndrome (WAS). The first attempts at gene therapy for WAS using a Upsilon-retroviral vector improved immunological param
Autor:
Upendra P. Hegde, Nicole Grant, Kieron Dunleavy, Richard F. Little, Armando C. Filie, John E. Janik, Seth M. Steinberg, Elaine S. Jaffe, Maryalice Stetler-Stevenson, Wyndham H. Wilson, Andrea Abati
Publikováno v:
Blood. 105:496-502
We assessed the cerebrospinal fluid (CSF) by flow cytometry and cytology in 51 newly diagnosed and 9 treated aggressive B-cell lymphomas at risk for central nervous system (CNS) involvement to examine the utility of flow cytometry, incidence of CSF d
Autor:
Guido Lucarelli, F Argiolu, Licinio Contu, Franco Locatelli, Maria Adele Sanna, Adriana Vacca, Piero De Stefano, Antonella Pizzati, M Arras, Antonio Ledda, Claudio Giardini, Giorgio La Nasa
Publikováno v:
Blood. 99:4350-4356
Allogeneic bone marrow transplantation (BMT) from a genotypically identical family donor is an accepted therapeutic option for homozygous beta-thalassemia. However, only a minority of patients have access to this curative procedure. The aim of this s
Autor:
Kathryn Evans, Raushan T. Kurmasheva, William R. Wilson, Donya Moradi Manesh, Ashlee Hedrick, Catherine A. Billups, Cara E. Toscan, Hernan Carol, Peter J. Houghton, Glenn M. Marshall, Jennifer Richmond, Rosemary Sutton, Lauryn S. Bracken, Jad El-Hoss, Malcolm A. Smith, Richard B. Lock
Publikováno v:
Blood. 126:1193-1202
PR-104, a phosphate ester of the nitrogen mustard prodrug PR-104A, has shown evidence of efficacy in adult leukemia clinical trials. Originally designed to target hypoxic cells, PR-104A is independently activated by aldo-keto-reductase 1C3 (AKR1C3).
Autor:
Paul Veys, Kanchan Rao, Su Han Lum, Prashant Hiwarkar, Robert Wynn, Ponni Sivaprakasam, Katharine Patrick, Juliana Silva, Sarah Lawson, Toni Petterson, Ciara O'Rafferty, Colin G. Steward, Persis Amrolia, Mary Slatter, Adam Gassas, Hemalatha Doss
Publikováno v:
Blood. 129(14)
Cidofovir is preemptively used for controlling adenoviremia and preventing disseminated viral disease in hematopoietic cell transplant (HCT) recipients but does not lead to resolution of viremia without T-cell immune-reconstitution. The lipid-conjuga