Zobrazeno 1 - 10
of 282
pro vyhledávání: '"11"'
Autor:
A M Smith, Linda M. Pilarski, P L Bergsagel, Michael J. Mant, Andrew R. Belch, Agnieszka J. Szczepek
Publikováno v:
Blood. 85:436-447
Multiple myeloma (MM) is characterized by a plasma cell infiltrate of the bone marrow (BM). However, late-stage monotypic B cells have been detected in the blood. This work analyzes the effects of clinical treatment on late stage CD19+ B cells presen
Publikováno v:
Blood. 104:1896-1896
Among the various chromosomal translocations found in pediatric pre-B cell acute leukemias, the t (4; 11) group contains patients of all ages as well as a clustering of children at birth or in the first year of life. As with all 11q23 abnormalities,
Autor:
Zuzana Zemanova, Christine Perot, Anna Leszl, Brian V. Balgobind, Akira Morimoto, Anne Auvrignon, Todd A. Alonzo, H. Berna Beverloo, Luca Lo Nigro, Jochen Harbott, Marry M. van den Heuvel-Eibrink, Erik Forestier, Jeffrey E. Rubnitz, C. Michel Zwaan, Irina Stasevich, Franklin O. Smith, Gertjan J.L. Kaspers, Martin Zimmermann, Nathalia Litvinko, Jan Stary, Ursula Creutzig, Christine J. Harrison, Sabine Strehl, Brenda Gibson, Susana C. Raimondi, Dirk Reinhardt, Takashi Taga, David Webb, Myron Chang, Henrik Hasle, Rob Pieters, Daisuke Tomizawa, Michael Dworzak, Nyla A. Heerema
Publikováno v:
Blood, 114(12), 2489-2496. American Society of Hematology
Balgobind, B V, Raimondi, S C, Harbott, J, Zimmermann, M, Alonzo, T A, Auvrignon, A, Beverloo, HB, Chang, M, Creutzig, U, Dworzak, M, Forestier, E, Gibson, B E, Hasle, H, Harrison, C, Heerema, N A, Kaspers, G J L, Leszl, A, Litvinko, N, Lo Nigro, L, Morimoto, A, Perot, C, Pieters, R, Reinhardt, D, Rubnitz, J E, Smith, F J, Stary, J, Stasevich, I, Strehl, S, Taga, T, Tomizawa, D, Webb, D F, Zemanova, Z, Zwaan, C M & van den Heuvel-Eibrink, M 2009, ' Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study ', Blood, vol. 114, no. 12, pp. 2489-2496 . https://doi.org/10.1182/blood-2009-04-215152
Balgobind, BV, Raimondi, SC, Harbott, J, Zimmermann, M, Alonzo, TA, Auvrignon, A, Beverloo, HB, Chang, M, Creutzig, U, Dworzak, MN, Forestier, E, Gibson, B, Hasle, H, Harrison, CJ, Heerema, NA, Kaspers, GJL, Leszl, A, Litvinko, N, Nigro, LL, Morimoto, A, Perot, C, Pieters, R, Reinhardt, D, Rubnitz, JE, Smith, FO, Stary, J, Stasevich, I, Strehl, S, Taga, T, Tomizawa, D, Webb, D, Zemanova, Z, Zwaan, CM & van den Heuvel-Eibrink, MM 2009, ' Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study ', Blood, vol. 114, no. 12, pp. 2489-96 . https://doi.org/10.1182/blood-2009-04-215152
Balgobind, B V, Raimondi, S C, Harbott, J, Zimmermann, M, Alonzo, T A, Auvrignon, A, Beverloo, HB, Chang, M, Creutzig, U, Dworzak, M, Forestier, E, Gibson, B E, Hasle, H, Harrison, C, Heerema, N A, Kaspers, G J L, Leszl, A, Litvinko, N, Lo Nigro, L, Morimoto, A, Perot, C, Pieters, R, Reinhardt, D, Rubnitz, J E, Smith, F J, Stary, J, Stasevich, I, Strehl, S, Taga, T, Tomizawa, D, Webb, D F, Zemanova, Z, Zwaan, C M & van den Heuvel-Eibrink, M 2009, ' Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study ', Blood, vol. 114, no. 12, pp. 2489-2496 . https://doi.org/10.1182/blood-2009-04-215152
Balgobind, BV, Raimondi, SC, Harbott, J, Zimmermann, M, Alonzo, TA, Auvrignon, A, Beverloo, HB, Chang, M, Creutzig, U, Dworzak, MN, Forestier, E, Gibson, B, Hasle, H, Harrison, CJ, Heerema, NA, Kaspers, GJL, Leszl, A, Litvinko, N, Nigro, LL, Morimoto, A, Perot, C, Pieters, R, Reinhardt, D, Rubnitz, JE, Smith, FO, Stary, J, Stasevich, I, Strehl, S, Taga, T, Tomizawa, D, Webb, D, Zemanova, Z, Zwaan, CM & van den Heuvel-Eibrink, MM 2009, ' Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study ', Blood, vol. 114, no. 12, pp. 2489-96 . https://doi.org/10.1182/blood-2009-04-215152
Translocations involving chromosome 11q23 frequently occur in pediatric acute myeloid leukemia (AML) and are associated with poor prognosis. In most cases, the MLL gene is involved, and more than 50 translocation partners have been described. Clinica
Autor:
Gordon W. Dewald, Rafael Fonseca, Richard J. Bailey, Kimberly J. Henderson, James D. Hoyer, Philip R. Greipp, Scott Van Wier, David P. Harrington, Emily A. Blood, Neil E. Kay, Brian G Van Ness, Robert A. Kyle, Martin M. Oken
Publikováno v:
Blood. 99:3735-3741
The t(11;14)(q13;q32) results in up-regulation of cyclin D1 and is the most common translocation detected in multiple myeloma, where it is also associated with a lymphoplasmacytic morphology. We performed an interphase fluorescent in situ hybridizati
Publikováno v:
Blood. 125:2875-2875
[Figure][1] A 48-year-old man with a history of diabetes was found to have an elevated serum immunoglobulin G (IgG) level (8.6 g/dL) during a routine blood workup. Further laboratory study and bone marrow biopsy confirmed IgG-κ type plasma cell myel
Autor:
Hervé Avet-Loiseau, Philippe Moreau, Richard Garand, Danielle Pineau, Régis Bataille, Nelly Robillard, Harousseau Jl, Marie-Josée Rapp
Publikováno v:
Blood. 102(3)
CD20 has been reinvestigated in 66 patients with multiple myeloma (MM). Twelve of the patients (18%) expressed CD20, including 5 of 50 patients at diagnosis presenting 100% CD20+ cells. Seven (58%) of 12 CD20+ patients with MM had a small mature plas
Autor:
Patrick Hagner, Anita Gandhi, Renee Yura, Sarah Hersey, Mingjun Zhang, Isaac Boss, Henry Chan, Falon D. Gray, Michelle Waldman
Publikováno v:
Blood. 134:1580-1580
B-cell maturation antigen (BCMA), a member of the TNF receptor superfamily, serves as the cell surface receptor for B-cell activating factor (BAFF). Upon binding of BAFF to BCMA, an intracellular signaling cascade is initiated resulting in upregulati
Autor:
Christopher Brown, Adam Brand, Qian Vicky Wu, Karen Spratt, Michael C. Jensen, Stephanie Mgebroff, Adam J. Lamble, Adam Johnson, Rebecca Gardner, Julie R. Park, Corinne Summers, Catherine Lindgren, Julie Rivers, Ashley Wilson, Colleen Annesley
Publikováno v:
Blood. 134:223-223
Background: While immunotherapy withCD19 specific CAR T cells for relapsed/refractory (R/R) B-ALL achieves MRD negative remission in nearly all patients, relapse occurs in approximately half of patients and is frequently associated with early loss of
Autor:
Hervé Dombret, Florent Dumezy, Xavier Thomas, Karine Celli-Lebras, Meyling Cheok, Claude Preudhomme, Adriana Plesa, Sandrine Hayette, Christophe Roumier, Yves Bertrand, Pierre Sujobert, Isabelle Tigaud, Delphine Manzoni
Publikováno v:
Blood. 132:4009-4009
Background: Clonal heterogeneity of the AML blast cell population has been well documented using next generation sequencing (NGS) strategies. This heterogeneity extends to the presence of LSC fraction among the leukemic population: a dynamic compartm
Autor:
Bing Z. Carter, Hongsheng Zhou, Linlin Zhou, Qifa Liu, Han He, Ya Gao, Rui Cao, Qiang Wang, Xiaoli Liu, Changxin Yin, Qiuli Li, Zhongxin Zhen, Dainan Lin
Publikováno v:
Blood. 132:4011-4011
Background Early T-cell precursor (ETP) lymphoblastic leukemia (ETP-ALL) is a neoplasm with an unique T-cell immunophenotype indicating limited early T differentiation. Ph-like ALL is a B-cell neoplasm which lack BCR-ABL1 translocation but similar ex