Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dan Li"'
Publikováno v:
Blood. 132:5100-5100
Purpose: Prognosis and therapeutic treatment of Fanconi anemia (FA) and acquired aplastic anemia (AA) are different. However, delayed and incorrect treatments are frequently occurred in FA because its symptoms are very similar to those of AA. This st
Autor:
Dan Li, Katherine Spokes, Shou-Ching S. Jaminet, Lauren Janes, William C. Aird, David L. Beeler, Joshua D. Smith, Peter Oettgen, Lei Yuan
Publikováno v:
Blood. 121:4404-4412
We previously demonstrated that the first intron of the human von Willebrand factor (vWF) is required for gene expression in the endothelium of transgenic mice. Based on this finding, we hypothesized that RNA splicing plays a role in mediating vWF ex
Autor:
Shou-Ching Shih, Ju Liu, Yoshiaki Okada, Erzsébet Ravasz Regan, Katherine Spokes, Takashi Minami, Dan Li, Enjing Jin, William C. Aird, Lauren Janes, David L. Beeler, Kiichiro Yano, Vesna Nikolova-Krstevski, Peter Oettgen, Lei Yuan, Jun-ichi Suehiro
Publikováno v:
Blood. 114:5557-5566
Vascular endothelial growth factor receptor 1 (VEGFR1) is a marker for endothelial-specific gene expression. We previously reported that the human VEGFR1 promoter (between −748 and +284) contains information for expression in the intact endothelium
Autor:
Liang Huang, Zhuoya Li, Qinlu Li, Lei Zhao, Jianfeng Zhou, Baihua Li, Shiqiu Zhou, Dan Li, Na Wang, Quan Gong, Li Zhu, Lili Gao, Jue Wang, Xiaoxi Zhou
Publikováno v:
Blood. 126(12)
To design an effective antibody therapy to improve clinical outcomes in leukemia, the identification of novel cell surface antigens is needed. Herein, we demonstrate a role for transmembrane tumor necrosis factor-α (tmTNF-α) in leukemia. To charact
Autor:
Han Liu, Jiong Hu, Xiaoyang Li, Junmin Li, Zhen Jin, Dan Li, Rufang Xiang, Yingxiao Wang, Molly Allen
Publikováno v:
Blood. 128:4190-4190
Background CD19-CAR T cells with costimulatory ligand of CD28 or 4-1BB have acquired well response in ALL and CLL, whereas it shows less effective in B-cell NHL. The microenvironment of lymphomas is much more complicated than that of leukemia, which
Autor:
Zhen Shao, Yuannyu Zhang, Jian Xu, Zhimin Gu, Xin Liu, Min Ni, Ralph J. DeBerardinis, Zeping Hu, Feng Zhou, Hui Cao, Dan Li, Robert A.J. Signer, Navdeep S. Chandel
Publikováno v:
Blood. 128:1038-1038
The developing hematopoietic system requires an exquisite coordination of gene expression and metabolism. Mitochondria are critical for heme and iron metabolism in erythroid cells, yet their regulation during normal erythropoiesis remains largely unk
Publikováno v:
Blood. 126:4300-4300
Cancer germline antigens (CGA) are expressed on several solid tumors including neuroblastoma. Their expression can be epigenetically upregulated upon treatment with decitabine (DAC), a demethylating chemotherapy drug. We have previously shown that DA
Autor:
Jian Xu, Guo-Cheng Yuan, Zhen Shao, Huafeng Xie, Luca Pinello, Woojin Kim, Stuart H. Orkin, Kimberly Glass, Dan Li, Jialiang Huang
Publikováno v:
Blood. 124:241-241
The epigenetic machinery plays crucial roles in hematopoiesis, and its deregulation drives the pathogenesis of blood disorders. Polycomb Repressive Complex 2 (PRC2) is a major class of epigenetic repressor that catalyzes the di/tri-methylation of his
Publikováno v:
Blood. 122:3802-3802
The Philadelphia chromosome is formed by a balanced, reciprocal translocation that pairs sequences from BCR on Chromosome 22 with sequences from ABL on Chromosome 9 and results in the production of the constituitively active tyrosine kinase Bcr-Abl.