Zobrazeno 1 - 10
of 33
pro vyhledávání: '"72"'
Autor:
Stéphanie Petit, Pierre Morel, Jenny Goudemand, Bénédicte Hivert, Claudine Caron, Corinne Fankam-Siaka, Olivier Tournilhac, Alain Duhamel, Cécile Charpy
Publikováno v:
Blood. 116:2438-2438
Abstract 2438 Introduction: Abnormalities of VWF have been described in WM pts, and several cases of AVWS have been reported. We aimed to describe the frequency of AVWS and the distributions of von Willebrand factor Ristocetin Cofactor activity (VWF:
Autor:
Olga K. Weinberg, Kai Fu, Stefano Monti, Zhang Xuan, Bruce A. Woda, Aliyah R. Sohani, Hongbo Yu, Daniel Gusenleitner, Ben Chen, Christopher D. Carey, Scott J. Rodig
Publikováno v:
Blood. 126:3903-3903
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL) have characteristic cellular, phenotypic, and genetic characteristics that reflect their distinctive biology. These distinctions are attributable, in part, to differential ac
Publikováno v:
Blood. 122:2365-2365
von Willebrand factor (VWF) is a large multimeric glycoprotein secreted from platelet α-granules and Weibel-Palade bodies of endothelial cells. VWF mediates the initial adhesion of platelets at sites of vascular injury and binds to and stabilizes bl
Publikováno v:
Blood. 122:3526-3526
Background and Objective Immune thrombocytopenia (ITP) is a typical autoimmune-mediated bleeding disorder in which isolated thrombocytopenia is resulted from increased platelet clearance and/or impaired thrombocytogenesis. In addition to producing an
Publikováno v:
Blood. 118:5004-5004
Abstract 5004 Introduction: Amiloride is an FDA approved potassium-sparing diuretic which targets Na+/H+ exchanger isoform 1 (NHE1). NHE1 is responsible for the regulation of the intracellular pH, as well as cell-cycle and apoptosis. In supra-pharmac
Autor:
Brian S. Zuckerbraun, Mitchell Dyer, Jay S. Raval, Shannon Haldeman, Matthew D. Neal, William E. Plautz, Marian A. Rollins-Raval, Jason L. Sperry, Francis X. Guyette
Publikováno v:
Blood. 136:9-9
Introduction: Increases in plasma von Willebrand Factor (vWF) antigen levels, accompanied by decreases in its respective metalloprotease, ADAMTS13, have been demonstrated following severe injury. We hypothesized that following traumatic injury, endot
Autor:
Marian A. Rollins-Raval, Brian S. Zuckerbraun, Jay S. Raval, Matthew D. Neal, Mitchell Dyer, Jason L. Sperry, Shannon Haldeman, William E. Plautz, Francis X. Guyette, Wyeth Alexander, Margaret V. Ragni
Publikováno v:
Blood. 134:444-444
Introduction: Increases in plasma von Willebrand Factor (vWF) levels, accompanied by decreases in its respective metalloprotease, ADAMTS13, have been demonstrated in diseases of microvascular injury. We hypothesized that following severe trauma, a bu
Publikováno v:
Blood. 69:1531-1534
Large multimers of von Willebrand factor (vWf) are released from the Weibel-Palade bodies (WPB) of cultured endothelial cells following treatment with a secretagogue, whereas predominantly dimeric forms are secreted constitutively. These two pools of
Autor:
Anna Kalota, Alan M. Gewirtz
Publikováno v:
Blood. 115:89-93
Biologic characterization of SB-559457 (SB), a nonpeptidyl hydrazone class of thrombopoietin receptor (Mpl) agonist, revealed toxicity toward human leukemia cells. Antiproliferative effects followed by significant, nonapoptotic, cell death within 72
Autor:
Annemieke G. Laarhoven, Rienk Y. J. Tamminga, Leendert Porcelijn, Masja de Haas, Nicole L. van Woerden, Marrie C. A. Bruin, Katja M. J. Heitink-Pollé, Cuno S.P.M. Uiterwaal, Judith Wesseling, Frans J. Smiers
Publikováno v:
Blood, 128(22):866. AMER SOC HEMATOLOGY
Background and objectives: Management in children with newly diagnosed immune thrombocytopenia (ITP) consists of careful observation or treatment with corticosteroids or intravenous immunoglobulin (IVIg). Observational studies suggest a lower risk of