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Autor:
Jürgen Krauter, Mark Ringhoffer, Arnold Ganser, Brigitte Schlegelberger, Daniela Späth, Marie von Lilienfeld-Toal, David Nachbaur, Hartmut Döhner, Veronica Teleanu, Gerhard Held, Michael Lübbert, Hans Martin, Verena I. Gaidzik, Gudrun Göhring, Sabine Kayser, Patricia Erdmann, Wolfgang Herr, Ulrich Germing, Mathias J. Rummel, Helmut R. Salih, Claus-Henning Köhne, Katharina Götze, H Salwender, Thomas Fischer, Richard F. Schlenk, Peter Paschka, Heinz A. Horst, Konstanze Döhner
Publikováno v:
Blood. 120:785-785
Abstract 785 Background: FLT3 internal tandem duplications (FLT3-ITD) occur in about 25% of acute myeloid leukemia (AML), are associated with cooperating gene mutations (NPM1, DNMT3A), and confer an adverse prognosis. Several studies have indicated t