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pro vyhledávání: '"Robert A. Lazarus"'
Autor:
Salina Louie, Shahram Misaghi, Cynthia Lam, Robert A. Lazarus, David E. Shaw, Lydia Santell, Brad Snedecor, Mandy Yim, Danming Tang, Pamela Chan, Blair Wilson
Publikováno v:
Biotechnology progress. 33(2)
While the most common causes of clonal instability are DNA copy number loss and silencing, toxicity of the expressed protein(s) may also induce clonal instability. Human DNase I (hDNase I) is used therapeutically for the treatment of cystic fibrosis