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Publikováno v:
Biotechnology Letters. 43:2199-2208
Nicotinamide mononucleotide (NMN) or Nicotinamide-1-ium-1-β-D-ribofuranoside 5'-phosphate is a nucleotide that can be converted into nicotinamide adenine dinucleotide (NAD) in human cells. NMN has recently attracted great attention because of its po
Publikováno v:
Biotechnology Letters. 43:1831-1844
Heparosan is used as the starting polysaccharide sulfated using sulfotransferase to generate fully elaborate heparin, a widely used clinical drug. However, the preparation of heparosan and enzymes was considered tedious since such material must be pr
Autor:
Daoyong Gong, Zhao Wenyan, Bochu Wang, Zhi Zhang, Liancai Zhu, Renfen Zha, Xinhua Meng, Yang Biling, Na Qi
Publikováno v:
Biotechnology Letters. 43:415-422
The comparative transcriptome analysis of the fungus Gibberella zeae which could efficiently catalyze the 7β-hydroxylation of LCA to produce UDCA was performed with LCA induction. This is the first time to report the comparative transcriptome of fun
Publikováno v:
Biotechnology Letters. 43:271-277
To produce high-, medium- and low-molecular-weight hyaluronic acid (HA) at different temperatures using engineered Bacillus subtilis expressing hyaluronidase (HAase) from leech. By overexpressing the HAase gene hya in the HA-producing strain WmB usin
Autor:
María Inés Infanzón-Rodríguez, María Guadalupe Aguilar-Uscanga, Juan Arturo Ragazzo-Sánchez, Montserrat Calderón-Santoyo, Sandra Del Moral
Publikováno v:
Biotechnology Letters. 42:2271-2283
To evaluate a strain of Fusarium verticillioides ITV03 isolated from wood residues in the Veracruz region of Mexico. Endoglucanase and β-glucosidase production by submerged fermentation was optimized using a Box–Behnken design, where the independe
Autor:
Chin Yin Khor, Boon Yin Khoo
Publikováno v:
Biotechnology Letters. 42:1581-1595
This study aimed to examine the metabolising effect of chrysin by investigating the mRNA expression levels of PPARα and its related cellular mechanisms in HCT116 cells. The mRNA expression of PPARα was significantly induced in HCT116 cells followin
Publikováno v:
Biotechnology Letters.
This study aimed to screen, characterize, and annotate the genome along with the comparison of GABA synthesis genes presented in lactic acid bacteria (LAB). Thirty-five LAB isolates from fermented foods were screened for GABA production using thin-la
Publikováno v:
Biotechnology Letters. 41:813-822
To explore the secondary metabolite biosynthetic potential of Rubrivivax benzoatilyticus JA2 using a new metabolite mining strategy. Combination of precursor-feeding and altered growth conditions were used to mine new biomolecules. Strain JA2 utilise
Autor:
Yanyun Hu, Zhiying Bian, Liyan Jia, Jun Wang, Yunliang Zhang, Chao Yin, Shuqin Guo, Ning Li, Jie Chen, Yanxin Xiao, Dongxun Zhang, Xincui Zhao
Publikováno v:
Biotechnology Letters. 39:1583-1590
To investigate the relationship between the serum level of miR-9 and the progression of diabetic nephropathy (DN) and related molecular mechanisms. Thirty-five healthy subjects and 140 DN patients were divided into five groups: control, DN I–II, DN
Autor:
Yixiang Xu, Xu Jiaqi, Wang Xudong, Jian Zhang, Boyang Yu, Xiu-Feng Liu, Chen Shen, Qianqian Wang, Yan Zhang
Publikováno v:
Biotechnology Letters. 39:1229-1235
To characterize glycosyltransferases from Bacillus subtilis ATCC 6633 and investigate their substrate specificity towards plant polyphenols. Among the cloned and expressed six UDP-glycosyltransferases (BsGT1-6), BsGT-1 showed activity with a wide ran