Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gerald A. Meininger"'
Autor:
Jared R. Tangney, Alice E. Zemljic-Harpf, Mariappan Muthuchamy, Jeffrey H. Omens, Lawrence R. Frank, Xin Wu, Joyce Chuang, Robert S. Ross, Peter Liao, Adarsh Krishnamurthy, Masahiko Hoshijima, Gerald A. Meininger, Andrew D. McCulloch, Matthew S. Janssen
Publikováno v:
Biophysical Journal. 104(7):1623-1633
Vinculin (Vcl) plays a key structural role in ventricular myocytes that, when disrupted, can lead to contractile dysfunction and dilated cardiomyopathy. To investigate the role of Vcl in myocyte and myocardial function, cardiomyocyte-specific Vcl kno
Autor:
Hongyu Qiu, William C. Hunter, Zhe Sun, Nancy L Sehgel, Jerome P. Trzeciakowski, Gerald A. Meininger, Dorothy E. Vatner, Shumin Gao, Stephen F. Vatner, Yi Zhu
Publikováno v:
Biophysical Journal. 102(3)
An increase in vascular stiffness is a fundamental component of hypertension. Our hypothesis is that the increased large artery stiffness in hypertension is due in part to intrinsic properties of vascular smooth muscle cells (VSMCs). Adult spontaneou
Publikováno v:
Biophysical Journal. 102(3)
Modification of proteins by non-enzymatic glycation occurs in diabetes mellitus, aging and pathological states including renal failure. Glycation reactions span early reversible reactions to irreversibly modified species termed advanced glycation end
Autor:
Zhe Sun, William C. Hunter, Dorothy E. Vatner, Nancy L. Sehgel, Jerome P. Trzeciakowski, Stephen F. Vatner, Yi Zhu, Gerald A. Meininger
Publikováno v:
Biophysical Journal. 106:356a
Hypertension and aging are both recognized to increase aortic stiffness, but the underlying mechanisms are not completely understood. Most prior studies have attributed increased aortic stiffness to mechanical changes within the extracellular matrix
Autor:
David J. Schmidt, Gerald A. Meininger, Edwin D.W. Moore, Lawrence M. Lifshitz, Frederic S. Fay
Publikováno v:
Biophysical Journal. (2):973-984
To localize activated protein kinase C (PKC) in smooth muscle cells, an antibody directed to the catalytic site of the enzyme was used to assess PKC distribution by immunofluorescence techniques in gastric smooth muscle cells isolated from Bufo marin