Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Giridhar A"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:2854-2862
Andrographolide, the major diterpenoidal constituent of Andrographis paniculata (Acanthaceae) and its derivatives have been reported to possess plethora of biological properties including potent anti-cancer activity. In this work, synthesis and in-vi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:5781-5786
Andrographolide, the major labdane diterpenoid from Andrographis paniculata has been reported to be cytotoxic against various cancer cells in vitro. Our research efforts led to the discovery of novel 12-phenyl thio and 12-aryl amino-14-deoxy-androgra
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:3959-3966
Multiple-targeted ligands can have certain advantages for the management of hypertension which has multiple controls. Molecules with dual bioactivities are available in literature for treating metabolic disorders like diabetes, hypertension and hyper
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:1821-1827
3D-QSAR analysis has been performed on a series of previously synthesized benzonitrile derivatives, which were screened as farnesyltransferase inhibitors, using comparative molecular field analysis (CoMFA) with partial least-square fit to predict the
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:3316