Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nobuhiro Hirai"'
Autor:
Yasushi Todoroki, Taku Muramatsu, Hajime Shimomura, Toshiyuki Ohnishi, Nobuhiro Hirai, Kotomi Ueno, Kenta Narita, Masaharu Mizutani
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:1743-1750
We prepared 19 amino acid conjugates of the plant hormone abscisic acid (ABA) and investigated their biological activity, enzymatic hydrolysis by a recombinant Arabidopsis amidohydrolases GST-ILR1 and GST-IAR3, and metabolic fate in rice seedlings. D
Autor:
Toshiyuki Ohnishi, Kotomi Ueno, Satoru Kondo, Hataitip Nimitkeatkai, Hikaru Aoyama, Taku Muramatsu, Masaharu Mizutani, Mariko Okazaki, Yasushi Todoroki, Nobuhiro Hirai
Publikováno v:
Bioorganic & Medicinal Chemistry. 19(1):406-413
We developed abscinazole-E1 (Abz-E1), a specific inhibitor of abscisic acid (ABA) 8'-hydroxylase (CYP707A). This inhibitor was designed and synthesized as an enlarged analogue of uniconazole (UNI), a well-known plant growth retardant, which inhibits
Autor:
Masaharu Mizutani, Saori Hiramatsu, Nobuhiro Hirai, Yasushi Todoroki, Mei-Hong Jin, Kyotaro Kobayashi, Bunta Watanabe, Hidetaka Yoneyama
Publikováno v:
Bioorganic & Medicinal Chemistry. 16(6):3141-3152
The plant growth retardant S-(+)-uniconazole (UNI-OH) is a strong inhibitor of abscisic acid (ABA) 8'-hydroxylase, a key enzyme in the catabolism of ABA, a plant hormone involved in stress tolerance, stomatal closure, flowering, seed dormancy, and ot
Publikováno v:
Bioorganic & Medicinal Chemistry. 15(18):6311-6322
Abscisic acid (ABA), a plant stress hormone, has a chiral center (C1′) in its molecule, yielding the enantiomers (1′S)-(+)-ABA and (1′R)-(−)-ABA during chemical synthesis. ABA 8′-hydroxylase (CYP707A), which is the major and key P450 enzyme
Autor:
Kanzo Sakata, Nobuhiro Hirai, Shigeki Saito, Yoshiharu Araki, Masaharu Mizutani, Kotomi Ueno, Yasushi Todoroki
Publikováno v:
Bioorganic & Medicinal Chemistry. 13(10):3359-3370
A major catabolic enzyme of the plant hormone abscisic acid (ABA) is the cytochrome P450 monooxygenase ABA 8′-hydroxylase. For designing a specific inhibitor of this enzyme, the substrate specificity and inhibition of CYP707A3, an ABA 8′-hydroxyl