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pro vyhledávání: '"Kevin D. Moeller"'
Autor:
Kevin D. Moeller, Garland R. Marshall, Chris M. W. Ho, Jill C. Simpson, Marvin C. Gershengorn, E.F. Berkley Shands
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:291-302
A modified synthetic route has been developed so that the steric size of constraints added to the pyroglutamate region of TRH (pGluHisProNH 2 ) can be varied. Both an analogue with a smaller ethylene bridge and a larger, more flexible propane bridge