Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rebecca Richards"'
Autor:
Alexandros D. Polydorides, Fan Zhang, Mark C. Pierce, Rebecca Richards-Kortum, Dongsuk Shin, Marion Anna Protano, Sharmila Ananadasabapathy
Publikováno v:
Biomedical Optics and 3-D Imaging.
This study introduces an approach for quantitative analysis of microendoscopic images to identify esophageal neoplasia. The approach quantifies morphologic parameters which distinguish esophageal neoplasia accurately in an independent validation set
Publikováno v:
Biomedical Optics and 3-D Imaging.
This is a proof-of-concept study to assess whether in vivo confocal microscopy coupled with topical proflavine staining can be used to recognize malaria-infected RBCs. Results from a chicken embryo model indicate this may be feasible.
Autor:
Ana Paula Benveniste, Savitri Krishnamurthy, Jessica Dobbs, Wei Yang, Henry Keurer, Hao Ding, Rebecca Richards-Kortum
Publikováno v:
Biomedical Optics and 3-D Imaging.
Confocal fluorescence microscopy can be used to rapidly acquire high resolution images of normal, benign, and neoplastic breast cellular features in ex vivo human breast tissue.
Publikováno v:
Biomedical Optics and 3-D Imaging.
Optical imaging of endogenous fluorophores and exogenous contrast agents can be used to assess changes in cellular metabolism and tumor microenvironment that relate to breast cancer progression.
Autor:
Sharmila Anandasabapathy, Mark C. Pierce, Peter K Thompson, Kelsey Rosbach, Rebecca Richards-Kortum, Nadhi Thekkek, Ann M. Gillenwater, Raymond Kaufman
Publikováno v:
Biomedical Optics and 3-D Imaging.
We have developed a high-resolution fluorescence microendoscope capable of imaging sub-cellular morphology in vivo, in real-time. We report our latest results in clinical studies for early cancer detection in the cervix, oral cavity, and esophagus.
Publikováno v:
Biomedical Optics and 3-D Imaging.
Three probes targeting molecular or morphologic characteristics of cancer were topically applied to freshly resected oral tissue. Optical contrast was used to predict the region of neoplasia; predicted regions agree well with histopathology maps.
Autor:
Wen Gao, Tao T. Le, Mark C. Pierce, Vijayashree S. Bhattar, Richard A. Schwarz, Vanda M. Stepanek, Rebecca Richards-Kortum, Darren Roblyer, Ann M. Gillenwater
Publikováno v:
Biomedical Optics and 3-D Imaging.
The diagnostic potential and clinical utility of widefield imaging and point spectroscopy are examined based on measurements of patients with precancerous or cancerous oral lesions. Portable clinical instruments for widefield imaging and spectroscopy
Publikováno v:
Biomedical Optics and 3-D Imaging.
Autor:
Noam Harpaz, Timothy J. Muldoon, Alexandros D. Polydorides, Rebecca Richards-Kortum, Sharmila Anandasabapathy, Dipen M. Maru, Nadhi Thekkek
Publikováno v:
Biomedical Optics and 3-D Imaging.
This ex vivo study evaluates widefield and high-resolution fluorescence imaging with vital-dye enhancement to improve endoscopic evaluation of metaplasia, dysplasia, and cancer in the gastrointestinal tract. Differences in epithelial features were ob
Autor:
Rebecca Richards-Kortum
Publikováno v:
Biomedical Optics and 3-D Imaging.
Multi-modal optical-imaging has potential to improve early detection of cancer in underserved populations. This talk will present a vision to expand the role of optical-imaging in global cancer management, highlighting recent widefield and high-resol