Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yuma Yamada"'
Publikováno v:
Biomaterials. 218
Nanomedicine promises to play an important role in next generation therapy, including Nucleic acid/Gene therapy. To accomplish this, innovative nanotechnologies will be needed to support nanomedicine by controlling not only the biodistribution but al
Publikováno v:
Biomaterials. 57:107-115
Mitochondrial genome-targeting nucleic acids are promising therapeutic candidates for treating mitochondrial diseases. To date, a number of systems for delivering genetic information to the cytosol and the nucleus have been reported, and several succ
Publikováno v:
Biomaterials. 136
Mitochondria have their own gene expression system that is independent of the nuclear system, and control cellular functions in cooperation with the nucleus. While a number of useful technologies for achieving nuclear transgene expression have been r
Autor:
Yuma Yamada, Hideyoshi Harashima
Publikováno v:
Biomaterials. 33:1589-1595
Mitochondrial dysfunction has been implicated in a variety of human diseases. It is now well accepted that mutations and defects in the mitochondrial genome form the basis of these diseases. Therefore, mitochondrial gene therapy and diagnosis would b
Publikováno v:
Biomaterials. 52
The cellular uptake pathway for a gene vector is an important factor in transgene expression. We previously constructed an original gene vector, multifunctional envelope-type nano device (MEND). The use of octaarginine (R8), a cell-penetrating peptid
Autor:
Yuta Ibayashi, Masatoshi Nomura, Shigeki Sasaki, Yukari Yasuzaki, Yuma Yamada, Mai Tabata, Atsushi Shibata, Hideyoshi Harashima, Yosuke Taniguchi
Publikováno v:
Biomaterials. 35(24)
Pancreatic beta cells secrete insulin in response to glucose levels and thus are involved in controlling blood glucose levels. A line of pancreatic beta cells "MIN6" has been used in studies related to the function of beta cells and diabetes therapy.