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Autor:
Steven N. Reuland, Nathaniel B. Goldstein, Katie A. Partyka, Shilo Smith, Yuchun Luo, Mayumi Fujita, Rene Gonzalez, Karl Lewis, David A. Norris, Yiqun G. Shellman
Publikováno v:
Biology Open, Vol 1, Iss 2, Pp 92-100 (2012)
Summary The BH3 mimetic ABT-737 is a potent inhibitor of the anti-apoptotic proteins Bcl-2, Bcl-XL, and Bcl-w. The Bcl-2 family modulates sensitivity to anticancer drugs in many cancers, including melanomas. In this study, we examined whether ABT-737
Externí odkaz:
https://doaj.org/article/f0a870b611c94139a97fd7b3100725a6