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Autor:
Rumiko Matsuoka, Nanako Kawaguchi, Toshio Nakanishi, Kei Inai, Daiji Takeuchi, Nobuhisa Hagiwara, Yoji Nagashima, Akiko Seki, Keisuke Okita, Emiko Hayama, Yoshiyuki Furutani
Publikováno v:
Biology, Vol 10, Iss 1062, p 1062 (2021)
Biology; Volume 10; Issue 10; Pages: 1062
Biology
Biology; Volume 10; Issue 10; Pages: 1062
Biology
Simple Summary In this study, the induced pluripotent stem cell-derived cardiomyocyte model from a patient with long QT syndrome harboring a heterozygous Nav1.5 R1623Q mutation exhibited prolonged field potential duration corrected by Fridericia’s
Autor:
S A Usanov, Alexey E. Medvedev, Evgeniy Yablokov, Yuri Mezentsev, P V Ershov, Aliaksandr Ya. Lushchyk, A. S. Ivanov, L. A. Kaluzhskiy, A. A. Gilep, A V Svirid, Arthur T. Kopylov
Publikováno v:
Biology, Vol 8, Iss 2, p 49 (2019)
Biology
Volume 8
Issue 2
Biology
Volume 8
Issue 2
Prostacyclin synthase (PTGIS
EC 5.3.99.4) catalyzes isomerization of prostaglandin H2 to prostacyclin, a potent vasodilator and inhibitor of platelet aggregation. At present, limited data exist on functional coupling and possible ways of regulat
EC 5.3.99.4) catalyzes isomerization of prostaglandin H2 to prostacyclin, a potent vasodilator and inhibitor of platelet aggregation. At present, limited data exist on functional coupling and possible ways of regulat
Publikováno v:
Biology
Biology, Vol 9, Iss 249, p 249 (2020)
Biology, Vol 9, Iss 249, p 249 (2020)
There is an under-recognized role of the aryl hydrocarbon receptor (AhR) in co-ordinating the entry and pathophysiology of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) that underpins the COVID-19 pandemic. The rise in pro-inflamma
Autor:
George Pentheroudakis, Joseph Sgouros, Dionysia Kolomodi, Maria Skondra, Dimitrios Dionysopoulos, George Fountzilas, Anna Koumarianou, Gregory Kaltsas, Dimitrios Pectasides, Georgia-Angeliki Koliou, Christos Poulios
Publikováno v:
Biology
Volume 9
Issue 3
Biology, Vol 9, Iss 3, p 51 (2020)
Volume 9
Issue 3
Biology, Vol 9, Iss 3, p 51 (2020)
The purpose of this study was to explore the efficacy and safety of everolimus administered as a first-line treatment in newly diagnosed patients with metastatic or inoperable gastroenteropancreatic neuroendocrine tumors (GEP NETs). This phase II, mu
Autor:
Raymond T. Cursons, Gregory M. Jacobson, Steve Bird, Linda M. Peters, Stephen O Evans, Michael B. Jameson
Publikováno v:
Biology, Vol 5, Iss 4, p 39 (2016)
Biology; Volume 5; Issue 4; Pages: 39
Biology
Biology; Volume 5; Issue 4; Pages: 39
Biology
DNA damage quantitation assays such as the comet assay have focused on the measurement of total nuclear damage per cell. The adoption of PCR-based techniques to quantify DNA damage has enabled sequence- and organelle-specific assessment of DNA lesion