Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michael J. Owens"'
Autor:
Zachary N. Stowe, Marc Kalin, Michael J. Owens, Jim Ritchie, Natalie J. Morris, D. Newport, Bettina T. Knight, Amy L. Cochran
Publikováno v:
Biological Psychiatry. 85:S319
Publikováno v:
Biological Psychiatry. 72:238-243
Background Neurochemical studies have pointed to a modulatory role in human aggression for a variety of central neurotransmitters; some seem to play an inhibitory role, whereas others seem to play a facilitory role in the modulation of aggression. La
Autor:
James C. Ritchie, Zachary N. Stowe, D. Jeffrey Newport, Michael J. Owens, Ada M. Loughhead, C. Lindsay DeVane
Publikováno v:
Biological Psychiatry. 59:287-290
Background The use of antidepressants during pregnancy continues to garner considerable attention, though there are limited investigations that have sought to quantify fetal exposure. Methods Maternal and umbilical cord sera were collected at deliver
Publikováno v:
Biological Psychiatry. 50:345-350
Single isomers of the selective serotonin reuptake inhibitors citalopram (escitalopram, S-citalopram) and fluoxetine (R-fluoxetine) are currently under development for the treatment of depression and other psychiatric disorders. Previous studies cond
Autor:
Leonard A. Rosenblum, Charles B. Nemeroff, Bruce Scharf, Jeremy D. Coplan, Michael J. Owens, Eric L. Smith, Jack M. Gorman, Margaret Altemus
Publikováno v:
Biological Psychiatry. 50:200-204
Background: The authors previously reported elevated cerebrospinal fluid (CSF) corticotropin-releasing factor (CRF) concentrations in juvenile primates nursed by mothers undergoing experimentally imposed unpredictable foraging conditions in compariso
Publikováno v:
Biological Psychiatry. 47:842-845
Background: The norepinephrine transporter (NET)/uptake site is an antidepressant-sensitive transporter located on plasma membranes of noradrenergic neurons and other specialized cells that remove norepinephrine (NE) from the synapse to terminate the
Autor:
Jay D. Kranzler, Susan J Plott, Srinivas G. Rao, Charles B. Nemeroff, S.Neil Vaishnavi, Michael J. Owens
Publikováno v:
Biological Psychiatry. 55:320-322
Background Though selective serotonin reuptake inhibitors have revolutionized the field of psychiatry with demonstrated efficacy in affective and anxiety disorders with minimal side effects, norepinephrine-serotonin reuptake inhibitors may provide ef
Publikováno v:
Biological Psychiatry. 48:954-956
Publikováno v:
Biological psychiatry. 50(11)
It has become increasingly clear that schizophrenia does not result from the dysfunction of a single neurotransmitter system, but rather pathologic alterations of several interacting systems. Targeting of neuropeptide neuromodulator systems, capable
Autor:
Robert T. Malison, Gerard Sanacora, Nallakandi Rajeevan, Gregory H. Pelton, Robert M Baldwin, John Seibyl, Michael J. Owens, Robert B. Innis, Robert M. Berman, Christopher H. van Dyck, Charles B. Nemeroff, Lawrence H. Price, Linda L. Carpenter, Dennis S. Charney
Publikováno v:
Biological psychiatry. 44(11)
Background: Prior research has suggested reductions in the density of serotonin transporter (SERT) binding sites in blood platelets and post-mortem brain tissue of depressed patients. We sought to determine whether patients with unipolar major depres