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pro vyhledávání: '"35"'
Publikováno v:
Biological Psychiatry. 71:611-617
Background Imaging studies have shown that major depressive disorder (MDD) is associated with altered activity patterns of the default mode network (DMN). However, the neural correlates of the resting-state DMN and MDD-related pathopsychological char
Autor:
Shan Xie, J. John Mann, Victoria Arango, Thomas B. Cooper, Suham Kassir, Basalingappa L. Hungund, K. Yaragudri Vinod
Publikováno v:
Biological Psychiatry. 57:480-486
Background: Alcoholism is often comorbid with mood disorders and suicide. We recently reported an upregulation of CB1 receptor-mediated signaling in the dorsolateral prefrontal cortex (DLPFC) of subjects with major depression who died by suicide. In
Autor:
Sue M. Cotton, Christos Pantelis, Lisa J. Phillips, Stephen J. Wood, Murat Yücel, Alex Fornito, Dennis Velakoulis, Patrick D. McGorry, Barnaby Nelson, Alison R. Yung
Publikováno v:
Biological psychiatry. 64(9)
Background Abnormalities of the anterior cingulate cortex (ACC) are frequently implicated in the pathophysiology of psychotic disorders, but whether such changes are apparent before psychosis onset remains unclear. In this study, we characterized pre
Autor:
Linda Spencer, Lawrence H. Staib, Jennifer A.Y. Johnston, Fei Wang, Brian Pittman, Pablo Najt, Xenophon Papademetris, Cheryl Lacadie, Elizabeth Lippard, Hilary P. Blumberg
Publikováno v:
Biological Psychiatry. 79:303-310
BACKGROUND: Increasing evidence supports a neurodevelopmental model for bipolar disorder (BD), with adolescence as a critical period in its development. Developmental abnormalities of anterior paralimbic and heteromodal frontal cortices, key structur
Publikováno v:
Biological Psychiatry. 74:490-501
Background Drug experimentation during adolescence is associated with increased risk of drug addiction relative to any other age group. To further understand the neurobiology underlying such liability, we investigate how early adolescent cocaine expe
Autor:
Andrew S. Fox, Steven E. Shelton, Heather C. Abercrombie, Ned H. Kalin, Terrence R. Oakes, Richard J. Davidson, Allison L. Jahn
Publikováno v:
Biological Psychiatry. 67:175-181
Background Hypothalamic-pituitary-adrenal (HPA) system activation is adaptive in response to stress, and HPA dysregulation occurs in stress-related psychopathology. It is important to understand the mechanisms that modulate HPA output, yet few studie
Autor:
Anderson Mon, Dieter J. Meyerhoff, Christoph Abé, Timothy C. Durazzo, Stefan Gazdzinski, Donna E. Murray
Publikováno v:
Durazzo, Timothy C; Meyerhoff, Dieter J; Mon, Anderson; Abé, Christoph; Gazdzinski, Stefan; & Murray, Donna E. (2016). Chronic Cigarette Smoking in Healthy Middle-Aged Individuals Is Associated With Decreased Regional Brain N-acetylaspartate and Glutamate Levels.. Biological psychiatry, 79(6), 481-488. doi: 10.1016/j.biopsych.2015.03.029. UCSF: Retrieved from: http://www.escholarship.org/uc/item/1sj3t99t
Biological psychiatry, vol 79, iss 6
Biological psychiatry, vol 79, iss 6
BACKGROUND: Cigarette smoking is associated with metabolite abnormalities in anterior brain regions, but it is unclear if these abnormalities are apparent in other regions. Additionally, relationships between regional brain metabolite levels and meas
Publikováno v:
Biological psychiatry. 70(9)
Background Environmental or genetic disturbances of early brain development are suggested to underlie the pathophysiology of several adult-onset neuropsychiatric disorders. We traced the developmental trajectories of brain structural and behavioral a