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Autor:
Huiwen Wang, Jian Zhang, Xiaoxun Zhang, Nan Zhao, Zongtao Zhou, Lijian Tao, Lei Fu, Shifang Peng, Jin Chai
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1868:166556
Cholestasis is characterized by intrahepatic accumulation of bile acids (BAs), resulting in liver injury, fibrosis, and liver failure. To date, only ursodeoxycholic acid and obeticholic acid have been approved for the treatment of cholestasis. As flu