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Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1865:129975
Introduction The endothelial glycocalyx is susceptible to high concentration of glucose and sodium in the blood. These challenges often involve an increase in osmotic pressure which may independently alters the glycocalyx components. The glycocalyx a
Publikováno v:
Biochimica et Biophysica Acta-General Subjects
Background: In eukaryotic cells, many proteins have to be transported across or inserted into the endoplasmic reticulum membrane during their biogenesis on the ribosome. This process is facilitated by the protein translocon, a highly dynamic multi-su
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1860:1877-1883
Non-invasive real time methods for characterizing biomolecular events that contribute towards apoptotic kinetics would be of significant importance in the field of cancer biology. Effective drug-induced apoptosis is an important factor for establishi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1864(No. 2):129329
Background Cell-based assays are essential for analyzing molecular functions and spatiotemporal information. The cell resealing technique, in which pore-forming toxins are used to permeabilize cell membranes, enables the delivery of various membrane-
Autor:
Nicolas Bourmeyster, Aurélie Mercier, Romain Clément, Patrick Bois, Aurélien Chatelier, Thomas Harnois
Publikováno v:
Biochimica et Biophysica Acta (BBA)-General Subjects
Biochimica et Biophysica Acta (BBA)-General Subjects, Elsevier, 2015, 1850 (6), pp.1215-1223. ⟨10.1016/j.bbagen.2015.02.009⟩
Biochimica et Biophysica Acta (BBA)-General Subjects, Elsevier, 2015, 1850 (6), pp.1215-1223. ⟨10.1016/j.bbagen.2015.02.009⟩
Background Like many voltage-gated sodium channels, the cardiac isoform Nav1.5 is well known as a glycoprotein which necessarily undergoes N-glycosylation processing during its transit to the plasma membrane. In some cardiac disorders, especially the
Autor:
Sergey Lukyanov, Natalia V. Klementieva, Boris E. Shakhov, Nadezhda I. Ignatova, Elena V. Zagaynova, Marina V. Shirmanova, Ludmila B. Snopova, Alina P. Ryumina, Ilya V. Turchin, Arkady F. Fradkov, Maria M. Kuznetsova, Konstantin A. Lukyanov, Ekaterina O. Serebrovskaya
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1830:5059-5067
Background Genetically encoded photosensitizers are a promising optogenetic instrument for light-induced production of reactive oxygen species in desired locations within cells in vitro or whole body in vivo. Only two such photosensitizers are curren
Autor:
Ludmila A. Baratova, Sergei A. Golyshev, Galina F. Sud'ina, Julia M. Romanova, Vladimir I. Stadnichuk, Natalia V. Fedorova, Svetlana I. Galkina, Marina V. Serebryakova, Thomas Klein
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1820:1705-1714
Background Following adhesion to fibronectin neutrophils can develop membrane tubulovesicular extensions (TVEs) that can be 200 nm wide and several cell diameters long. TVEs attach neutrophils to the other cells, substrata or bacteria over distance.
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1820:1383-1390
Background Galectins have been identified as modulators of many monocyte/macrophage functions. In the response to a wide range of environmental cues macrophages may exhibit different biochemical and biological characteristics, but two main subtypes,
Autor:
Pen Hui Yin, Chew Wun Wu, Kuo Hung Huang, Chin-Wen Chi, Hsin Chen Lee, Anna Fen Yau Li, Hwa Li Kao, Wen Yi Hung
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1820:1102-1110
Background Mitochondrial dysfunction has been shown to promote cancer cell migration. However, molecular mechanism by which mitochondrial dysfunction enhances gastric cancer (GC) cell migration remains unclear. Methods Mitochondria specific inhibitor
Publikováno v:
Biochimica et Biophysica Acta (BBA)-General Subjects; Vol 1820
Background Galectin-3 (the Mac-2 antigen) is abundantly expressed in both macrophage like cells and certain non-macrophage cells. We have studied endocytosis of galectin-3 as one important step relevant for its function, and compared it between varia