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pro vyhledávání: '"Susan P. Lees-Miller"'
Autor:
Icy D’Silva, Damien D'Amours, Jean Lagueux, Joëlle D. Pelletier, Susan P. Lees-Miller, Michael Weinfeld, M.Ahmad Chaudhry, Guy G. Poirier
Publikováno v:
Biochimica et biophysica acta. 1430(1)
Poly(ADP-ribose) polymerase (PARP) and DNA-dependent protein kinase (DNA-PK) are important nuclear enzymes that cooperate to minimize genomic damage caused by DNA strand interruptions. DNA strand interruptions trigger the ADP-ribosylation activity an