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Publikováno v:
Biochimica et biophysica acta. 1813(1)
The physiological responses of AMPA receptors can be modulated through the differential expression of their subunits and by modifying their number at the cell surface. Here we have studied the expression of AMPA receptor subunits (GluR1–4) mRNAs in
Autor:
Anastasia A. Chupyrkina, S. S. Jankauskas, Egor Y. Plotnikov, Dmitry B. Zorov, Vladimir P. Skulachev, Irina B. Pevzner, Denis N. Silachev
Publikováno v:
Biochimica et biophysica acta. 1812(1)
Oxidative stress-related renal pathologies apparently include rhabdomyolysis and ischemia/reperfusion phenomenon. These two pathologies were chosen for study in order to develop a proper strategy for protection of the kidney. Mitochondria were found
Autor:
Patrick Yu-Wai-Man, Wolfram S. Kunz, David C. Samuels, Rita Horvath, Patrick F. Chinnery, Joanna Stewart, Kerstin Hallmann, Susanne Schoeler, Robert W. Taylor, Kamil S. Sitarz, Angela Pyle
Publikováno v:
Biochimica et biophysica acta. 1812(3)
Disorders of mitochondrial DNA (mtDNA) maintenance have emerged as an important cause of human genetic disease, but demonstrating the functional consequences of de novo mutations remains a major challenge. We studied the rate of depletion and repopul
Publikováno v:
Dentistry Publications
Background The mechanisms underlying the effect of alterations in type I collagen on bone mechanical properties are not well defined. In a previous study, male and female emu tibiae were endocortically treated with 1 M potassium hydroxide (KOH) solut
Autor:
Elodie Bedu, Oscar Puig, Roger Meurer, Silvi Luell, Lynn S. Gerckens, Jayne Chin, John S. Mudgett, Ester Carballo-Jane, Daniel Blom, Mohammed Selloum, Ting-Ting Yamin, Marie-France Champy
Publikováno v:
Biochimica et biophysica acta. 1801(12)
The purinergic receptor P2Y13 has been shown to play a role in the uptake of holo-HDL particles in in vitro hepatocyte experiments. In order to determine the role of P2Y13 in lipoprotein metabolism in vivo, we ablated the expression of this gene in m
Autor:
Valentina Perrone, Giuseppe Genchi, Attilio Pingitore, Mariarita Perri, Erika Cione, Emma Vilardi
Publikováno v:
Biochimica et biophysica acta. 1800(9)
Background Vitamin A is suggested to be protective against oxidative stress. However, different authors observed pro-oxidant effects of retinoids both in experimental works and clinical trials. These discordances are the bases for the investigation o
Autor:
Johanna E. M. Groener, Gabor E. Linthorst, Machtelt G. Bouwman, Frits A. Wijburg, C. E. M. Hollak, Sijmen Kuiper, A. H. Zwinderman, Johannes M. F. G. Aerts, M.A. van den Bergh Weerman, Saskia M. Rombach, Nick Dekker, Ben J. H. M. Poorthuis
Publikováno v:
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1802(9), 741-748. Elsevier
Biochimica et Biophysica Acta: Molecular Basis of Disease, 1802(9), 741-748
Biochimica et Biophysica Acta: Molecular Basis of Disease, 1802(9), 741-748
Fabry disease is an X-linked lysosomal storage disorder due to deficiency of alpha-Galactosidase A, causing accumulation of globotriaosylceramide and elevated plasma globotriaosylsphingosine (lysoGb3). The diagnostic value and clinical relevance of p
Publikováno v:
Biochimica et Biophysica Acta-Molecular Cell Research, 1813(2), 346-357. Elsevier
Decreasing the temperature to 30 C is accompanied by significant enhancement of alpha(2C)-AR plasma membrane levels in several cell lines with fibroblast phenotype, as demonstrated by radioligand binding in intact cells. No changes were observed on t
Autor:
Susana Cadenas, Enara Aguirre
Publikováno v:
Biochimica et biophysica acta. 1797(10)
The lipid peroxidation product 4-hydroxynonenal (HNE) increases the proton conductance of the inner mitochondrial membrane through effects on uncoupling proteins (UCPs) and the adenine nucleotide translocase (ANT); however, the relative contribution
Publikováno v:
Biochimica et biophysica acta. 1800(9)
Background Nitric oxide (NO) plays a vital role in maintaining the survivability of circulating erythrocytes. Here we have investigated whether NO depletion associated with visceral leishmaniasis (VL) is responsible for the reduced survival of erythr