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Autor:
Nicolás Octavio Favale, Norma B. Sterin-Speziale, Bruno Jaime Santacreu, Lucila Gisele Pescio, María Gabriela Márquez
Publikováno v:
Biochimica et biophysica acta. 1861(6)
Phosphatidylcholine (PC) is the main constituent of mammalian cell membranes. Consequently, preservation of membrane PC content and composition - PC homeostasis - is crucial to maintain cellular life. PC biosynthetic pathway is generally controlled b
Publikováno v:
Biochimica et biophysica acta. 1820(10)
Background Lead (Pb) exposure is considered as a risk factor for the development of renal dysfunction. The flavonoid quercetin (QE) in diets exerts the nephroprotective effects. This study investigated the effects of quercetin on renal oxidative stre
Autor:
Robert M. Sargis, Brian A. Neel, Yuxi Lin, Clifton O. Brock, Allison T. Hickey, Matthew J. Brady, Daniel A. Carlton
Publikováno v:
Biochimica et biophysica acta. 1822(6)
Emerging data suggest that environmental endocrine disrupting chemicals may contribute to the pathophysiology of obesity and diabetes. In a prior work, the phenylsulfamide fungicide tolylfluanid (TF) was shown to augment adipocyte differentiation, ye
Publikováno v:
Biochimica et biophysica acta. 1813(1)
The physiological responses of AMPA receptors can be modulated through the differential expression of their subunits and by modifying their number at the cell surface. Here we have studied the expression of AMPA receptor subunits (GluR1–4) mRNAs in
Publikováno v:
Biochimica et Biophysica Acta-Molecular Cell Research, 1813(2), 346-357. Elsevier
Decreasing the temperature to 30 C is accompanied by significant enhancement of alpha(2C)-AR plasma membrane levels in several cell lines with fibroblast phenotype, as demonstrated by radioligand binding in intact cells. No changes were observed on t
Publikováno v:
Biochimica et biophysica acta. 1801(4)
The ability of n-3 PUFA to competitively inhibit the use of arachidonic acid (AA) for membrane phospholipid synthesis and prostaglandin E(2) (PGE(2)) production has been well demonstrated in single cell models. In the present study, we investigated t
Autor:
Amedeo Carraro, Mario A. Pagano, G. Nalesso, Francesco D'Amico, Umberto Cillo, Enrico Gringeri, Antonio Toninello, Anna Maria Brunati, Maria Lina Massimino, Elena Tibaldi
Publikováno v:
Biochimica et biophysica acta. 1783(3)
Platelet-derived growth factor (PDGF) has been shown to be essential in the activation of hepatic stellate cells (HSCs), contributing to the onset and development of hepatic fibrosis. Recently, sphingosine-1-phosphate (S1P) has been shown to be a mit
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1772(9), 1065-1074. Elsevier Science
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2007, 1772 (9), pp.1065. ⟨10.1016/j.bbadis.2007.05.002⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2007, 1772 (9), pp.1065. ⟨10.1016/j.bbadis.2007.05.002⟩
Anthracycline antibiotics (e.g. doxorubicin and daunorubicin) are among the most effective and widely used anticancer drugs. Unfortunately, their clinical use is limited by the dose-dependent cardiotoxicity. Flavonoids represent a potentially attract
Publikováno v:
Biochimica et biophysica acta. 1687(1-3)
Conjugated linoleic acids (CLAs), tetradecylthioacetic acid (TTA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are all shown to differently affect lipid homeostasis. Additionally, previous studies have shown that introducing a methyl g
Publikováno v:
Biochimica et biophysica acta. 1583(3)
The aim of this paper was to ascertain whether chronic pretreatment with thioacetamide (TAA) might alter the uptake of a load of retinol and dolichol distribution in hepatocytes (HC), hepatic stellate cells (HSC) (Ito-1 and Ito-2 subfractions), Kupff