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Autor:
A. van Tol, Albert K. Groen, S. E. Borggreve, Robin P. F. Dullaart, R. de Vries, Geesje M. Dallinga-Thie, Bruce H. R. Wolffenbuttel
Publikováno v:
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1781(1-2), 10-15. Elsevier
Biochimica et biophysica acta-Molecular and cell biology of lipids, 1781(1-2), 10-15. ELSEVIER SCIENCE BV
Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1781(1-2), 10-15. Elsevier
Biochimica et biophysica acta-Molecular and cell biology of lipids, 1781(1-2), 10-15. ELSEVIER SCIENCE BV
Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1781(1-2), 10-15. Elsevier
A recent population-based study showed that cholesteryl ester transfer protein (CETP) gene variations, which relate to lower plasma CETP, may predict increased cardiovascular risk, in spite of higher HDL cholesterol. Among other functions, CETP activ
Autor:
Sophie Lestavel, Olivier Briand, Christopher Knouff, Véronique Clavey, Nobuyo Maeda, Michael K. Altenburg
Publikováno v:
Biochimica et biophysica acta. 1684(1-3)
Differences in affinity of human apolipoprotein E (apoE) isoforms for the low density lipoprotein receptor (LDLR) are thought to result in the differences in lipid metabolism observed in humans with different APOE genotypes. Mice expressing three com
Autor:
Christopher F. Higgins, Christiane Albrecht, James S. Owen, Simon W Davies, Michael D. Feher, Emily R. Eden, Kevin C.R. Baynes, Anne K. Soutar, Silke Schepelmann, Alessandro Sardini
Publikováno v:
Biochimica et biophysica acta. 1689(1)
Extremely low concentrations of high density lipoprotein (HDL)-cholesterol and apolipoprotein (apo) AI are features of Tangier disease caused by autosomal recessive mutations in ATP-binding cassette transporter A1 (ABCA1). Less deleterious, but domin
Publikováno v:
Biochimica et biophysica acta. 324(1)
Homologous DNA from a human lymphoblastoid cell line is taken up in macromolecular form by human skin fibroblasts in culture. Experiments utilizing the heavy buoyant density and ultraviolet-light sensitivity of DNA containing 5-bromouracil reveal tha
Publikováno v:
Biochimica et biophysica acta. 450(3)
Human skin fibroblasts in culture served as a model system to study intracellular cholesterol ester deposition in mesenchymal cells. Confluent cultures were exposed to homologous low density lipoprotein alone and together with chloroquine. In the pre
Publikováno v:
Biochimica et biophysica acta. 454(3)
Cultured fibroblasts grown in monolayer were incubated for a short time with radioactively labeled microbial DNA and diethylaminoethyl-dextran (DEAE-dextran), poly-L-lysine, or calcium phosphate, agents previously demonstrated by others to markedly e
Autor:
W. Mangels, C. R. Bartram, C. C. Schürer, Hansruedi Glatt, H. W. Rüdiger, Franz Oesch, F. V. Kohl
Publikováno v:
Biochimica et biophysica acta. 609(2)
Benzo[a]pyrene 4,5-oxide was covalently bound to DNA of cultured human fibroblasts and caused sister chromatid exchange. The monooxygenase inhibitor α-napthoflavone suppressed this induction of sister chromatic exchange, but did not affect binding t
Autor:
Sandra Czekanski, Mark J. Poznansky
Publikováno v:
Biochimica et biophysica acta. 685(2)
Cholesterol readily exchanges between human skin fibroblasts and unilamellar phospholipid vesicles. Only a fraction of the exchangeable cholesterol and only 10-15% of the total cellular free cholesterol is available for net movement or depletion to c
Publikováno v:
Biochimica et biophysica acta. 451(1)
Choleragen increases cyclic AMP content of confluent human fibroblasts. Maximally effective concentrations of isoproterenol and prostaglandin E1 also induce large increases in cyclic AMP content of human fibroblasts and in confluent cultures the effe
Publikováno v:
Biochimica et biophysica acta. 578(2)
Bovine and human epidermal cells were cultured on mitomycin C treated fibroblasts. The cells were carried through four passages and found to synthesize fibrous proteins and insoluble cell envelopes. Acid buffer soluble fibrous protein, prekeratin, an