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Publikováno v:
Biochimica et biophysica acta. 1778(10)
The calcium-sensing receptor (CaR) is expressed on intestinal epithelial serosal membrane and in Caco-2 cells. In renal epithelium, CaR expressed on the basolateral membrane acts to limit excess tubular Ca2+ reabsorption. Therefore, here we investiga
Publikováno v:
Biochimica et biophysica acta. 1564(2)
Placental transfer of maternal calcium (Ca 2+ ) is a crucial step for fetal development although the biochemical mechanisms responsible for this process are largely unknown. This process is carried out in vivo by the placental syncytiotrophoblast lay
Publikováno v:
Biochimica et biophysica acta. 1223(2)
A moderate sustained rise in intracellular ionised calcium has been observed to be associated with apoptosis occurring in many experimental systems. The application of extracellular and intracellular chelators of calcium has been reported to produce
Publikováno v:
Biochimica et biophysica acta. 1147(1)
Sodium fluoride (NaF) alone below the concentration of 10 mM had no effect on platelet intracellular Ca2+ ([Ca2+]i). When platelets were incubated with low concentrations of NaF (10 mM) prior to thrombin stimulation, the second phase of [Ca2+]i eleva
Autor:
Søren Risom Kristensen
Publikováno v:
Biochimica et biophysica acta. 1091(3)
Calcium has been suggested to be the final common mediator of cell damage, but conflicting reports to prove this hypothesis have appeared. In order to elucidate the role of calcium in cell damage caused by ATP depletion, the effect of addition of cal
Publikováno v:
Biochimica et biophysica acta. 1053(1)
A rise in the cytosolic free Ca2+ concentration due to both mobilization of Ca2+ from internal stores and influx of extracellular Ca2+ across the plasma membrane through ‘second messenger-operated Ca2+ channels’ is one of the first transmembrane
Publikováno v:
Biochimica et biophysica acta. 763(3)
The ability of C5a to stimulate lysosomal enzyme release and 45Ca2+ efflux from rabbit neutrophils was studied. C5a stimulated β-glucuronidase release from cytochalasin B-treated neutrophils either in the presence or absence of extracellular calcium
Autor:
Birthe Foder, Ole Scharff
Publikováno v:
Biochimica et biophysica acta. 861(3)
The net Ca 2+ influx was increased in human red cells in suspension by adding moderate concentrations of the Ca 2+ ionophore A23187, and due to the increased cellular Ca 2+ concentration ([Ca] i ) the K + channels opened (the ‘Gardos effect’). At
Autor:
R. Grant, Michael J. Dunn
Publikováno v:
Biochimica et biophysica acta. 352(1)
1. 1. Progressive reductions of extracellular Na + (Na O + ) reduced radioisotopic Na + efflux from human erythrocytes in the presence of ouabain. Nine different counter-ions were used to replace Na 0 + and the results were qualitatively similar. 2.
Publikováno v:
Biochimica et biophysica acta. 1010(3)
Inositol phosphate formation in response to cholinergic stimulation was studied in cultured human sweat duct cells, prelabelled with myo-[2-3H]inositol. Formation of inositol mono-, bis-, tris- and tetrakisphosphates was increased after 15 min stimul