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Autor:
Daniel Gagiannis, Werner Reutter, Reinhart Gossrau, Martin Zimmermann-Kordmann, Rüdiger Horstkorte
Publikováno v:
Biochimica et biophysica acta. 1770(2)
Sialic acids play an important role during development, regeneration and pathogenesis. The precursor of most physiological sialic acids, such as N -acetylneuraminic acid is N -acetyl- d -mannosamine. Application of the novel N -propanoylmannosamine l
Autor:
Kenichi Mishima, Shinji Soeda, Michihiro Fujiwara, Yukihiro Shoyama, Katsunori Iwasaki, Hiroyuki Tanaka, Reiko Eyanagi, Hiroshi Shimeno, Akihisa Toda, Takashi Ochiai
Publikováno v:
Biochimica et biophysica acta. 1770(4)
Crocus sativus L. (saffron) has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne or tranquilizer. Our previous study demonstrated that crocin, a carotenoid pigment of saffron, can su
Autor:
Ira Probodh, Linda J. Johnston, Nongnuj Tanphaichitr, Wattana Weerachatyanukul, Kessiri Kongmanas
Publikováno v:
Biochimica et biophysica acta. 1768(2)
Sulfogalactosylglycerolipid (SGG) is found in detergent-resistant lipid raft fractions isolated from sperm plasma membranes and has been shown to be important in sperm–egg adhesion. In order to provide more direct evidence for the association of su
Autor:
Durval Rosa Borges, Fernando G. Agostino, José Eduardo P. Pouza, Priscila Mimary, Marcia R. Nagaoka, Maria Kouyoumdjian, Luciana Gomiero, Felipe Oliveira Teixeira
Publikováno v:
Biochimica et biophysica acta. 1760(12)
Bradykinin elicits an intrahepatic vascular response (IHVR) mediated by the constitutive B 2 receptor (B 2 R). The biological effects of kinins may also be mediated by the inducible B 1 receptor (B 1 R). Aim: To verify if the hepatic B 1 R expression
Autor:
Yuji Furukawa, Michio Komai, Naofumi Takumi, Yusuke Ohsaki, Kousaku Ohinata, Hitoshi Shirakawa, Yoshihiko Minegishi, Takeo Mizutani
Publikováno v:
Biochimica et biophysica acta. 1760(10)
Vitamin K (K) is an essential factor for the posttranslational modification of blood coagulation factors as well as proteins in the bone matrix (Gla proteins). It is known that K is not only distributed in the liver and bones but also abundantly dist
Autor:
Spyros S. Skandalis, M. Stavropoulos, Dora Kyriakopoulou, Dimitrios A. Theocharis, Dimitris Kletsas
Publikováno v:
Biochimica et biophysica acta. 1760(8)
Pancreatic carcinoma (PC) is a cancer type with highly malignant growth and dissemination pattern of which the mechanisms are poorly understood. However, the malignant phenotype is closely linked to extracellular matrix (ECM) of which proteoglycans (
Publikováno v:
Biochimica et biophysica acta. 1760(3)
Elongation Factor-2 (eEF-2) is the protein that catalyzes the translocation of the ribosome through mRNA. Not all oxidants affect eEF-2, which is extremely sensitive to oxidative stress caused mainly by lipid peroxidant compounds such as cumene hydro
Autor:
Andreas Schäffler, Christa Büchler, Markus Neumeier, J. Schölmerich, Hans H Herfarth, Alois Fürst
Publikováno v:
Biochimica et biophysica acta. 1732(1-3)
Genomic structure, promoter region, amino acid sequence and exon-specific primer combinations of the human omentin gene are presented. Omentin mRNA expression differs between omental adipose tissue probes from patients with chronic inflammatory bowel
Publikováno v:
Biochimica et biophysica acta. 1760(2)
The principal objective of this study was to investigate the mechanisms regulating the activity of gamma-glutamylcysteine ligase (GCL; EC 6.3.2.2), the rate limiting enzyme in glutathione biosynthesis. Two phylogenetically divergent species, mouse an
Publikováno v:
Biochimica et biophysica acta. 1760(2)
In the present study, we have demonstrated the suitability of microspheres in removal of plasma bilirubin from systemic circulation of hyperbilirubinemic rats. Poly (lactide co-glycolide) microspheres (PLGA microspheres) have been shown to bind with