Zobrazeno 1 - 10
of 206
pro vyhledávání: ''
Publikováno v:
Biochimica et biophysica acta. 1393(1)
The present study investigates the effects of various glutathione (GSH) depleting agents on sn-glycerol-3-phosphate acyltransferase (GPAT) activity, the first committed step in adipose triacylglycerol formation. GPAT activity was measured in the pres
Publikováno v:
Biochimica et biophysica acta. 1349(3)
Thia fatty acids are fatty acid analogues, where sulfur atoms substitute methylene groups in the carbon chain. In 7800 C1 Morris hepatoma cells and in hepatocytes 9-thia and 10-thia stearic acid are strong inhibitors of stearoyl-Co desaturase, while
Publikováno v:
Biochimica et biophysica acta. 1349(2)
Activity of cholinephosphate cytidylyltransferase, the rate-limiting enzyme in phosphatidylcholine synthesis, increases rapidly in the lung after birth predominantly due to an increase in membrane-associated activity. Although there is strong evidenc
Autor:
Devanand L. Luthria, Howard Sprecher
Publikováno v:
Biochimica et biophysica acta. 1346(3)
According to the revised pathways of polyunsaturated fatty acid biosynthesis three, rather than two acids, must be chain elongated for converting linoleate and linolenate, respectively, to 22:5(n-6) and 22:6(n-3) (Sprecher et al. (1995) J. Lipid Res.
Autor:
Carlos P. Sotomayor, Horacio A. Garda, Felipe Aguilar, Marco A. Soto, Rodolfo R. Brenner, Ana M. Bernasconi
Publikováno v:
Biochimica et biophysica acta. 1323(1)
The influence of a fat-free diet on the lipid dynamics of rat liver microsomes and liposomes of microsomal lipids was studied by using different fluorescence methods. Lifetime distribution and rotational diffusion of probes with different localizatio
Publikováno v:
Biochimica et biophysica acta. 1290(3)
Mouse liver microsomes oxidized linoleic acid to form 9,10- or 12,13-epoxyoctadecenoate. These monoepoxides were subsequently hydrolyzed to their corresponding diols in the absence of the microsomal epoxide hydrolase inhibitor, 1,2-epoxy-3,3,3-trichl
Autor:
John Edgar Smith, Steven J. Ritter
Publikováno v:
Biochimica et biophysica acta. 1290(2)
N-(4-Hydroxyphenyl)retinamide (HPR; Fenretinide), a synthetic retinoid possessing antitumor activity, depresses plasma retinol and retinol-binding protein (RBP) concentrations. In study 1, the ability of retinol or HPR to induce RBP secretion from th
Publikováno v:
Biochimica et biophysica acta. 1299(1)
Alkyl gallate, which is known as an antioxidant, intensively inhibited delta 5 and delta 6 desaturation in both rat liver microsomes and an arachidonic acid-producing fungus Mortierella alpina 1S-4. The rat liver microsomal delta 5 and delta 6 desatu
Publikováno v:
Biochimica et biophysica acta. 1292(1)
A new method of assay for the delta 6-desaturation of linoleic acid was developed. This method, which uses HPLC for separation of the fatty acid substrate and product, exhibited a lower coefficient of variation (0.3%) than the reported TLC method (3.
Autor:
James M. Trzaskos, Young Ki Paik, Tae Neung Johng, James L. Gaylor, Chap Ki Kim, Kye Im Jeon, Dong Min Lim
Publikováno v:
Biochimica et biophysica acta. 1259(1)
We have previously characterized the membrane-bound sterol 14-reductase (14-reductase) that catalyzes anaerobically NADPH-dependent reduction of the 14-double bond of delta 8,14-diene or delta 7,14-diene sterols that are sterol intermediates in chole