Zobrazeno 1 - 10
of 119
pro vyhledávání: ''
Publikováno v:
Biochimica et biophysica acta. 1813(1)
The physiological responses of AMPA receptors can be modulated through the differential expression of their subunits and by modifying their number at the cell surface. Here we have studied the expression of AMPA receptor subunits (GluR1–4) mRNAs in
Publikováno v:
Biochimica et biophysica acta. 1800(9)
Background Nitric oxide (NO) plays a vital role in maintaining the survivability of circulating erythrocytes. Here we have investigated whether NO depletion associated with visceral leishmaniasis (VL) is responsible for the reduced survival of erythr
Autor:
Antonio Carlos dos Santos, Carlos Curti, Fernando P. Rodrigues, Carlos Henrique Tomich de Paula da Silva, Cezar R. Pestana, Sérgio Akira Uyemura, Gilberto L. Pardo-Andreu
Publikováno v:
Biochimica et biophysica acta. 1787(3)
The oxidation of critical cysteines/related thiols of adenine nucleotide translocase (ANT) is believed to be an important event of the Ca 2+ -induced mitochondrial permeability transition (MPT), a process mediated by a cyclosporine A/ADP-sensitive pe
Autor:
Eishun Tsuchida, Keitaro Sou
Publikováno v:
Biochimica et biophysica acta. 1778(4)
Anionic vesicles containing acidic phospholipids are known complement activators. To clarify which negative physicochemical electrostatic charges on vesicles and structural specificities of acidic lipids are critical to complement activation, the ele
Publikováno v:
Biochimica et biophysica acta. 1349(3)
Although lysophosphatidylcholine (lyso-PtdCho) accumulates in the sarcolemmal (SL) membrane and alters its function during myocardial ischemia and diabetic cardiomyopathy, the effects of lyso-PtdCho on SL signalling processes have not yet been invest
Publikováno v:
Biochimica et biophysica acta. 1290(2)
Recent evidence suggests that a melatonin (MEL) mechanism of action may be through modulation of Ca2+-activated calmodulin (CaM). MEL binds to CaM with a high affinity, and has been shown to act as a CaM antagonist. Among the CaM-dependent enzymes, C
Publikováno v:
Biochimica et biophysica acta. 1257(3)
Arachidonoylethanolamide or 'anandamide' is a naturally occurring derivative of arachidonic acid that has been shown to activate cannabinoid receptors in the brain. Its metabolic inactivation by brain tissue has been investigated. Anandamide is hydro
Autor:
Marcelo Hermes-Lima, Anibal E. Vercesi, AndréR. Meinicke, Valderez G.R. Valle, Roger F. Castilho, Etelvino J. H. Bechara
Publikováno v:
Biochimica et biophysica acta. 1188(1-2)
Reactive oxygen species (ROS) generated by metal-catalyzed 5-aminolevulinic acid (ALA) aerobic oxidation have been shown to damage the inner membrane of isolated rat liver mitochondria by a Ca(2+)-dependent mechanism. The present work describes exper
Publikováno v:
Biochimica et biophysica acta. 1220(3)
The effect of high and low pH on anoxic cell injury was studied in freshly isolated rat hepatocytes cast in agarose gel threads and perfused with Krebs-Henseleit bicarbonate buffer (KHB) saturated with 95% O2 and 5% CO2. Cytosolic free calcium (Ca2+i
Publikováno v:
Biochimica et biophysica acta. 1158(3)
Oxygen-derived radicals have been suggested to produce tissue injury during endotoxic shock by initiating lipid peroxidation. In order to investigate the induction of lipid peroxidation by Escherichia coli 0111:B4 lipopolysaccharide (LPS) on hepatocy