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Autor:
Douglas Borchman, Zofia Hetman
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 21, Iss, Pp-(2020)
Biochemistry and Biophysics Reports, Vol 21, Iss, Pp-(2020)
Background With dry eye, the ratio of cholesteryl ester (CE) to wax ester (WE) decreases substantially in meibum, but the functional and structural consequences of this change are speculative. The aim of this study is to confirm this finding and to b
Autor:
Vidushi Asati, Pankaj Kumar Sharma
Publikováno v:
Biochemistry and Biophysics Reports, Vol 20, Iss, Pp-(2019)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
A β-glucosidase with high specific activity towards isoflavone glycosidic conjugates was purified from seeds of Guar (Cyamopsis tetragonoloba) by ammonium sulphate precipitation followed by size exclusion and ion exchange chromatography. The pH and
Publikováno v:
Biochemistry and Biophysics Reports, Vol 14, Iss C, Pp 98-103 (2018)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Oxidized cholesterol has been widely reported to contribute to the pathogenesis of Alzheimer's disease (AD). However, the mechanism by which they affect the disease is not fully understood. Herein, we aimed to investigate the effect of 7-ketocholeste
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 147-153 (2017)
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 147-153 (2017)
Formation of neutrophil extracellular traps (NETs) can perpetuate sterile inflammation; thus, it is important to clarify their pathophysiological characteristics. Free heme, derived via hemolysis, is a major contributor to organ damage, and reportedl
Autor:
Akihiro Tai, Kaori Miura
Publikováno v:
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 232-236 (2017)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Ascorbic acid (AA) has been reported as a treatment for cancer patients. Intravenous (iv) administration of high-dose AA increases plasma AA levels to pharmacologic concentrations and generates reactive oxygen species (ROS) to exert anti-tumor activi
Publikováno v:
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 133-139 (2017)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Phospholipases D (PLDs) catabolize structural phospholipids to produce phosphatidic acid (PtdOH), a lipid playing central role in signalling pathways in animal, yeast and plant cells. In animal cells two PLD genes have been studied while in model pla
Publikováno v:
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 106-113 (2017)
Biochemistry and Biophysics Reports
BIOCHEMISTRY AND BIOPHYSICS REPORTS
Biochemistry and Biophysics Reports
BIOCHEMISTRY AND BIOPHYSICS REPORTS
In stressed plants, the reactive oxygen species (ROS) levels rise. Key to ROS signaling research are detection and identification of the protein cysteine sulfenylation (-SOH), the ROS-mediated oxidative product of a thiol (-SH). Arabidopsis thaliana
Autor:
Marigo Stathis, Ajit G. Thomas, Brent R. Stockwell, Barbara S. Slusher, Mariana Figuera-Losada, Camilo Rojas
Publikováno v:
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 266-272 (2017)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
The inflammatory response in the central nervous system involves activated microglia. Under normal conditions they remove damaged neurons by phagocytosis. On the other hand, neurodegenerative diseases are thought to involve chronic microglia activati
Publikováno v:
Biochemistry and Biophysics Reports
We present a simple method for efficient DNA ligation utilizing the heat generation of ferromagnetic particles subjected to an ac magnetic field. We carry out the ligation of DNA fragments with cohesive ends using T4 DNA ligase immobilized on the sur
Autor:
Chelliah Jayabaskaran, K. Akhilender Naidu, Maheswaraiah Anikisetty, Tirumala Harikrishna Anantha Krishna, William R Surin, Subban Kamalraj
Publikováno v:
Biochemistry and Biophysics Reports, Vol 18, Iss, Pp-(2019)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Retinoic acid, a derivative of vitamin A, is known to possess in vivo anti-inflammatory, anti-platelet and fibrinolytic activities. We have investigated the in vitro thrombin and platelet aggregation inhibitory activities of vitamin A (retinol) and i