Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Malcolm, C."'
Publikováno v:
Biochemical Pharmacology; 2001, Vol. 62 Issue: 4 p431-438, 8p
Publikováno v:
Biochemical Pharmacology. 20:3077-3089
A study was made of the biliary excretion of 14 C-pentaerythritol trinitrate in the rat to elucidate the possible role of enterohepatic circulation in the prolonged action of the drug. The biliary drug excretion consisted entirely of metabolites whic
Publikováno v:
Biochemical Pharmacology. 18:1985-1990
Rats were studied after being given a single dose of 14C-pentaerythritol trinitrate by gavage. The labeled components of the blood, urine and gastrointestinal tract were identified by thin-layer chromatography and assayed quantitatively by radioscann
Publikováno v:
Biochemical Pharmacology. 16:309-316
Radioactive pentaerythritol tetranitrate (PETN) was administered orally to rats, and its absorption, tissue distribution, and excretion were followed at specified time intervals. By applying thin-layer chromatography and radio-scanning techniques, th
Autor:
Myriam D. Melgar, J.Krystyna Karpowicz, Frederick J. Di Carlo, Barry Dubinsky, Malcolm C. Crew
Publikováno v:
Biochemical pharmacology. 24(2)
The analgesic ED 50 of tilidine administered orally to rats was 15.4 mg/kg at 15 min and 17.2 mg/kg at 30 min. The drug was metabolized quickly and extensively, and it and its principal metabolite readily crossed the blood-brain barrier. Analgesia af
Publikováno v:
Biochemical pharmacology. 17(10)
The metabolism of 14 C-labeled glyceryl trinitrate was studied in the rat. Absorption, tissue distribution and elimination were followed after administering a single dose by gavage. Thin-layer chromatography and radio-scanning methods were employed t
Publikováno v:
Biochemical Pharmacology. 16:1147-1148
Autor:
Dubinsky, Barry, Crew, Malcolm C., Melgar, Myriam D., Karpowicz, J.Krystyna, Di Carlo, Frederick J.
Publikováno v:
In Biochemical Pharmacology 1975 24(2):277-281
Publikováno v:
In Biochemical Pharmacology 1991 41(9):1351-1360
Publikováno v:
In Biochemical Pharmacology 1971 20(11):3077-3089