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Autor:
Henry M. Staines, Kiaran Kirk
Publikováno v:
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Parasitized erythrocytes from mice infected with the murine malaria parasite Plasmodium v inckei v inckei showed a marked increase in the rate of influx of choline compared with erythrocytes from uninfected mice. In contrast, uninfected erythrocytes
Autor:
E D Saggerson, N Alam
Publikováno v:
Biochemical Journal. 334:233-241
1. Rat soleus strips were incubated with 5 mM glucose, after which tissue metabolites were measured. Alternatively, muscle strips were incubated with 5 mM glucose and 0.2 mM palmitate, and the formation of 14CO2 from exogenous palmitate or from fatty
Publikováno v:
Biochemical Journal. 318:981-987
To clarify the mechanism of exocytosis in neurotransmitter release, the fusion of synaptic vesicles with presynaptic membranes prepared from rat brain synaptosomes and concomitant acetylcholine (ACh) release induced by fusion of them were studied in
Publikováno v:
Biochemical Journal. 317:167-172
We have demonstrated previously that glucose activates the multifunctional Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) in isolated rat pancreatic islets in a manner consistent with a role of this enzyme in the regulation of insulin se
Autor:
Armando A. Genazzani, Antony Galione
Publikováno v:
Biochemical Journal. 315:721-725
Nicotinic acid–adenine dinucleotide phosphate (NAADP) is a novel intracellular Ca2+ releasing agent recently described in sea-urchin eggs and egg homogenates. Ca2+ release by NAADP is independent of that induced by either inositol trisphosphate (In
Publikováno v:
Biochemical Journal. 315:679-686
Lipopolysaccharide (LPS), the major cell wall constituent of Gram-negative bacteria, evokes a multitude of biological effects in mammals including pyrogenicity and toxic shock syndrome. Polymyxin B (PmB), a polycationic cyclic peptide, is known to ne
Publikováno v:
Biochemical Journal. 310:449-452
In the absence of extracellular Ca2+, extensive Ca2+ release from the platelet intracellular stores [monitored as an increase of intracellular Ca2+ concentration ([Ca2+]i)] is produced by the combined action of the endomembrane Ca(2+)-ATPase inhibito
Publikováno v:
Biochemical Journal. 310:67-72
Lipoprotein lipase (LPL) activity is reduced in cardiomyocytes from rat hearts following the acute (4-5 day) induction of diabetes with 100 mg/kg streptozotocin. The molecular basis for this inhibitory effect of diabetes on LPL activity was investiga
Publikováno v:
Biochemical Journal. 308:399-404
In TEA3A1 rat thymic epithelial cells, ATP stimulates prostaglandin E2 (PGE2) production through activation of phospholipase A2 (PLA2) enzymic activity. The stimulation of PGE2 production tested with other nucleotides indicated the agonist potency of
Autor:
Michael F. Scully, S. Bokkala, C A Goodwin, Sholeh Namiranian, K. S. Authi, V. V. Kakkar, Caroline P.D. Wheeler-Jones
Publikováno v:
Biochemical Journal. 308:15-21
One of the essential roles for platelets in haemostasis is in the potentiation of blood clotting due to the contribution of anionic phospholipid from the surface of the cells, as an essential cofactor to the proteolytic reactions of coagulation (plat