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Autor:
Xinrui Zhao, Yuexin Jin, Zhongmin Tian, Yanan Ouyang, Xuewei Zheng, Pengfei Yang, Lan Chen, Li Zeng, Meng Chen
Publikováno v:
Biochemical and Biophysical Research Communications. 533:188-194
Aims Dahl salt-sensitive (SS) rats develop similar prediabetes lesion characteristics, such as impaired glucose tolerance (IGT), when compared with the salt resistant rat. In this study, we evaluate the risk of high glucose intake during prediabetes
Publikováno v:
Biochemical and Biophysical Research Communications. 523:315-321
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disease for which specific biomarkers and pathological mechanisms have yet to be identified. Methylphenidate (MPH) is commonly used to treat ADHD, but its therapeutic mechanisms
Autor:
Miaomiao Fan, Shan Wang, Tao Yin, Xiong Wang, Wenjun Yan, Ling Zhang, Yi Liu, Huishou Zhao, Congye Li, Ling Tao
Publikováno v:
Biochemical and Biophysical Research Communications. 516:1103-1109
Atherosclerosis is characterized by the accumulation of excess cholesterol in plaques. Reverse cholesterol transport (RCT) plays a key role in the removal of cholesterol. In the present study, we examined the effect of thioredoxin-1 (Trx-1) on RCT an
Publikováno v:
Biochemical and biophysical research communications. 572
Previous study documented that Lactobacillus paracasei S0940 and Streptococcus thermophilus ldbm1 have obvious cholesterol-lowering abilities in vitro. In this study, the safety of two strains were evaluated by nitroreductase test, hemolysis test and
Publikováno v:
Biochemical and Biophysical Research Communications. 516:812-818
Proteinuria is an important marker and is closely related to the progressive decline of renal function. Our previous research showed that angiopoietin-like-3 (ANGPTL3) plays a crucial role in proteinuria. In this study, we prepared an antibody agains
Autor:
Hui Liang, Yutong Wang
Publikováno v:
Biochemical and Biophysical Research Communications. 498:473-480
Abnormal lipid metabolism may contribute to the pathogenesis of non-alcoholic steatohepatitis (NASH). The ATP-binding cassette transporter A1 (ABCA1) protein mediates the transport of cholesterol and phospholipids from cells to apolipoprotein A-I (ap
Scavenger receptor class B type 1 regulates neuroblastoma cell proliferation, migration and invasion
Autor:
Marlyn Panchoo, Andras G. Lacko
Publikováno v:
Biochemical and Biophysical Research Communications. 495:614-620
Neuroblastoma (NB) is an extra cranial pediatric embryonal tumor most prevalent in children less than 1 year of age. NB accounts for 7% of all pediatric cancers but accounts for 15% of all childhood cancer deaths. Scavenger receptor class B type 1 (S
Publikováno v:
Biochemical and Biophysical Research Communications. 474:554-559
Obesity is associated with hyperlipidemia, electrical remodeling of the heart, and increased risk of supraventricular arrhythmias in both male and female patients. The delayed rectifier K+ current (IK), is an important regulator of atrial repolarizat
Publikováno v:
Biochemical and biophysical research communications. 504(2)
Diabetes mellitus is a chronic metabolic disorder characterized by rise in blood glucose levels and generation of free radicals which could induce mitochondrial membrane permeability transition (MMPT) pore opening. This study examined the in vivo act
Publikováno v:
Biochemical and biophysical research communications. 501(4)
Probiotics such as Lactobacillus and Bifidobacterium improve the balance of intestinal microflora and have various physiological functions beneficial to human health. It is not always known whether the ingested microbial cells are viable- or killed.