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Autor:
Hossein Dinpanah, Mostafa Zare, Farimah Beheshti, Zahra Baradaran, Milad Hashemzehi, Arefeh Vakilian, Mahmoud Hosseini
Publikováno v:
Behavioural brain research. 411
Objective Adolescence is a crucial time for brain maturation. We investigated the protective effects of metformin (Met) on behavioral changes, oxidative stress, tumor necrosis factor alpha (TNF-α) and nitrite in adulthood induced by ethanol (Eth) co
Autor:
Cristian Gerónimo-Olvera, Lucía Quevedo-Corona, Mireya Alcaraz-Zubeldia, Francisca Pérez-Severiano, Juan Carlos Martínez-Lazcano, Alicia Sánchez-Mendoza, M. Alejandra Hernández-Melesio, Camilo Ríos, María E. Jiménez-Capdeville, Martha E. Santoyo-Pérez
Publikováno v:
Behavioural Brain Research. 366:108-117
Nitric oxide (NO) plays a leading role in learning and memory processes. Previously, we showed its ability to modify the deleterious effect of immunotoxin 192 IgG-saporin (192-IgG-SAP) in the cholinergic system. The aim of this study was to analyze t
Autor:
Junliang Hao, Francesco Matrisciano, Kjell A. Svensson, Lakshmi Rajagopal, Herbert Y. Meltzer, Mei Huang
Publikováno v:
Behavioural Brain Research. 361:139-150
Diminished dopamine D1 stimulation may contribute to cognitive impairment in Alzheimer's and Parkinson's diseases, schizophrenia, and other neuropsychiatric disorders. However, orthosteric D1 receptor (D1R) agonists produce receptor desensitization a
Publikováno v:
Behavioural Brain Research. 361:159-166
One-trial contextual fear conditioning in laboratory mice results in a fear memory which is relatively specific to the original conditioning context shortly after conditioning but becomes more unspecific after an incubation time of one month. This pr
Publikováno v:
Behavioural Brain Research. 348:139-149
Acute stress influences learning and memory in humans and rodents, enhancing performance in some tasks while impairing it in others. Typically, subjects preferentially employ striatal-mediated stimulus-response strategies in spatial memory tasks foll
Publikováno v:
Behav Brain Res
Peripheral and central administration of glucose potently enhance cognitive functions. The present experiments examined changes in brain extracellular glucose levels while rats were trained to solve hippocampus-sensitive place or striatum-sensitive r
Autor:
David F Barnard, Sachi Chaudhari, Adam Kulp, Devanshi M. Mehta, Brett M Lowden, Cassidy A. Ridley, James Krzoska, John D. Johnson
Publikováno v:
Behav Brain Res
Following a stressful event, the hypothalamus-pituitary-adrenal axis mediates the release of the stress hormone cortisol (corticosterone in rodents; CORT). Elevated CORT binds to glucocorticoid receptors to mediate physiological responses including f
Publikováno v:
Behavioural Brain Research. 347:167-174
Taking into account the rather frequent concomitance of nicotine abuse and stress, we aimed to research memory- and depression-related effects of nicotine administration in combination with chronic mild unpredictable stress (CMUS) in mice and an invo
Autor:
Samaneh Dehghan, Manouchehr Ashrafpour, Arghavan Afghani, Alireza Mousavi Majd, Fereshteh Pourabdolhossein, Mohammad Gol, Sahand Ashrafpour, Forough Ebrahim Tabar
Publikováno v:
Behavioural Brain Research. 336:111-121
Cognitive impairment and memory deficit are common features in multiple Sclerosis patients. The mechanism of memory impairment in MS is unknown, but neuroimaging studies suggest that hippocampal demyelination is involved. Here, we investigate the rol
Autor:
Kinzo Matsumoto, Hironori Fujiwara, Ryota Araki, Takeshi Yabe, Ken Ebihara, Dya Fita Dibwe, Suresh Awale
Publikováno v:
Behavioural Brain Research. 334:6-15
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with core symptoms of social impairments and restrictive repetitive behaviors. Recent evidence has implicated a dysfunction in the GABAergic system in the pathophysiology of ASD. We inve