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Autor:
Yanli Zhang, Fengrui Cao, Qing Liu, Shansong Yi, Jianmei Ma, Xiaohan Yang, Xinsheng Li, Fenghua Xu, Kai Fan, Gang Liu, Xinnan Zhao, Guoyang Xu
Publikováno v:
Behavioural Brain Research. 364:494-502
The immuno-inflammatory activation triggered by various stresses play an important role in pathophysiology of depression. The immune responses display differential pathological characters in different stresses. However, comparative data and analysis
Autor:
Xiao-Yu Yin, Xiu Yang, Can Gao, Le Liu, Han Gao, Jing-Ru Hao, Qi-Kai Tang, De-Qin Geng, Wei Wang, Luo-Yue Yin
Publikováno v:
Behavioural Brain Research. 364:75-84
Chronic stress is an important factor for depression. Most individuals recover from stress, while some develop into depression. The pathogenesis of resilience or susceptibility remains unclear. Stress activates the hypothalamic-pituitary-adrenal (HPA
Publikováno v:
Behavioural Brain Research. 361:159-166
One-trial contextual fear conditioning in laboratory mice results in a fear memory which is relatively specific to the original conditioning context shortly after conditioning but becomes more unspecific after an incubation time of one month. This pr
Autor:
Robert Lalonde, Guillaume Harlé, Jean-Pol Frippiat, Catherine Strazielle, Coralie Fonte, Armelle Ropars
Publikováno v:
Behavioural Brain Research
Behavioural Brain Research, Elsevier, 2017, 326, pp.121-131. ⟨10.1016/j.bbr.2017.02.035⟩
Behavioural Brain Research, Elsevier, 2017, 326, pp.121-131. ⟨10.1016/j.bbr.2017.02.035⟩
Receptors for glucocorticoid (GR) and corticotropin-releasing hormone (CRH) are largely found in brain sensorimotor structures, particularly in cerebellum, underlining a potential role of stress hormones in the regulation of motor function. Since CRH
Autor:
Ying Chen, Wen-Jun Su, Yong-Jie Lian, Chun-Lei Jiang, Zili You, Guo-Cai Lu, Hong Gong, Shijie Feng, Ying Zong, Yun-Zi Liu, Wei Peng, Yi Zhang, Yun-Xia Wang
Publikováno v:
Behavioural Brain Research. 322:1-8
Background Abundant researches indicate that neuroinflammation has important roles in the pathophysiology of depression. Our previous study found that the NLRP3 inflammasome mediated stress-induced depression-like behavior in mice via regulating neur
Publikováno v:
Behavioural Brain Research. 314:96-105
Prenatal alcohol exposure can produce permanent alterations in brain structure and profound behavioral deficits. Mouse models can help discover mechanisms and identify potentially useful interventions. This study examined long-term influences of eith
Autor:
Bartłomiej Pochwat, Agata Krakowska, Gabriel Nowak, Bożena Muszyńska, Anna Rafało-Ulińska, Bernadeta Szewczyk, Kristina Friedland, Włodzimierz Opoka
Publikováno v:
Behavioural brain research. 372
Chronic unpredictable mild stress (CUMS) - a rodent model of depression mimics a variety of neurochemical and behavioral alterations similar to those seen in human depression. This study evaluated the antidepressant activity of hyperforin in the CUMS
Publikováno v:
Behavioural brain research. 364
Background At present, the harm of new-type drug, methamphetamine (METH), has gradually exceeded that of the traditional opioid drugs, and METH abuse has become a serious public health and social problem. In our previous study, complement factor H (C
Autor:
Benjamin K. Yee, Lianteng Zhi, Hansruedi Büeler, Wayne A. Cass, Liuke Sun, Ruifang Shen, Sandeep Kumar Agnihotri, Marilyn J. Duncan, Ravi Shankar Akundi
Publikováno v:
Behavioural brain research. 363
Parkinson's disease (PD) is characterized by motor impairments and several non-motor features, including frequent depression and anxiety. Stress-induced deficits of adult hippocampal neurogenesis (AHN) have been linked with abnormal affective behavio
Autor:
Xin Jiang, Yanqiu Jia, Jing Xu, Yining Xiao, Mingyue Fan, Wei Jin, Nan Meng, Yu Yin, Haifeng Zhao, Peiyuan Lv
Publikováno v:
Behavioural Brain Research. 291:399-406
Lithium has been reported to have neuroprotective effects, but the preventive and treated role on cognition impairment and the underlying mechanisms have not been determined. In the present study, C57Bl/6 mice were subjected to repeated bilateral com