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Autor:
Aya Kadota, Akemi Kakino, Tomonori Okamura, Akira Fujiyoshi, Aya Hirata, Yoko Usami, Keiko Kondo, Katsuyuki Miura, Yoshiko Fujita, Tatsuya Sawamura, Takashi Hisamatsu, Hirotsugu Ueshima, Hiroyoshi Segawa
Publikováno v:
Atherosclerosis. 313:20-25
Background and aims Dysfunctional high-density lipoprotein (HDL) is a risk factor for cardiovascular disease (CVD) beyond HDL concentrations. Recently, a novel method has been introduced to measure LOX-1 ligand containing apolipoprotein AI (LAA), whi
Autor:
Barbara Dietel, Miyuki Tauchi, Gerhard Krönke, Fabian Seibert, Christoph J. Binder, Jochen A. Ackermann, Maria Oszvar-Kozma, Katharina Hofheinz, Hartmut Kühn, Georg Schett
Publikováno v:
Atherosclerosis. 311:67-72
Background and aims Oxidation of low-density lipoprotein (LDL) and oxidized LDL-mediated activation of the innate immune system have been recognized as early key events during the pathogenesis of atherosclerosis. Recent evidence identified eosinophil
Autor:
Philip J. Barter, Ben J. Wu, Kwok Leung Ong, Matthew J. Budoff, Robyn L. McClelland, Bradley Tucker, Matthew A. Allison, Kerry-Anne Rye
Publikováno v:
Atherosclerosis. 299:38-44
Non-alcoholic fatty liver disease (NAFLD) is associated with inflammation and atherogenic lipoprotein abnormalities. Previous studies suggest an association of fibroblast growth factor 21 (FGF21) with NAFLD. Therefore, we assessed the association of
Autor:
Xia Meng, Hao Li, Jinxi Lin, Yilong Wang, Yongjun Wang, Anxin Wang, Nan Zhang, Guojuan Chen, Liye Dai, Yingting Zuo
Publikováno v:
Atherosclerosis. 297:74-80
Low-density lipoprotein (LDL) and oxidized low-density lipoprotein (oxLDL) levels are thought to be related to recurrent stroke. However, the joint association of circulating LDL and oxLDL levels with the outcomes of acute minor ischemic stroke and t
Autor:
Parveen K. Garg, Steven Shea, Matthew A. Allison, James H. Stein, Laurent Yvan-Chavret, Robyn L. McClelland, Neal W. Jorgensen, Alan R. Tall
Publikováno v:
Atherosclerosis
Background and aims We aimed to assess the relationship of HDL (high-density lipoprotein)-mediated cholesterol mass efflux capacity (CMEC) with risk of incident peripheral artery disease (PAD). Methods CMEC was measured in 1458 Multi-Ethnic Study of
Autor:
Chao-Ke Tang, Wei Xie, Duo Gong, Da-Wei Zhang, Xiaoyan Dai, Zhen-Wang Zhao, Liang Li, Weidong Yin, Yun-Cheng Lv, Min Zhang, Xi-Long Zheng, Dongming Guo
Publikováno v:
Atherosclerosis. 289:143-161
Background and aims Kruppel-like factor 14 (KLF14) is known to play a role in atherosclerosis, but the underlying mechanisms are still largely unknown. The aim of our study was to explore the effects of KLF14 on lipid metabolism and inflammatory resp
Autor:
Rieko Isoda, Kiminori Hosoda, Mariko Harada-Shiba, Atsushi Takahashi, Yoshihiro Miyamoto, Mika Hori, Masatsune Ogura, Cheol Son, Suguru Yamamoto, Hiroaki Masuda, Naotaka Ohta
Publikováno v:
Atherosclerosis. 289:101-108
Background and aims More than 4970 variants in the low-density lipoprotein receptor (LDLR) gene and 350 variants in the proprotein convertase subtilisin/kexin 9 (PCSK9) gene have been reported in familial hypercholesterolemia (FH) patients. However,
Autor:
Shuangyuan Wang, Yuhong Chen, Yufang Bi, Mian Li, Kui Peng, Min Xu, Weiqing Wang, Yu Xu, Jieli Lu, Xueyan Wu, Chunyan Hu, Jie Zhang, Rui Du
Publikováno v:
Atherosclerosis. 289:8-13
Epidemiological evidence on the association between elevated lipoprotein (a) (Lp (a)) with risk of stroke remains inconsistent. We aimed to investigate the association between serum Lp (a) level and the risk of stroke among middle-aged and elderly Ch
Autor:
Preman Kumarathurai, Christian Anholm, Sten Madsbad, Olav W. Nielsen, Rosemary L. Walzem, Lene Rørholm Pedersen, Mogens Fenger, Amirsalar Samkani, Ahmad Sajadieh, Ole Peter Kristiansen, Steen B. Haugaard
Publikováno v:
Atherosclerosis. 288:60-66
Background and aims Atherosclerosis in obesity and type 2 diabetes (T2DM) is associated with low-grade inflammation (LGI) and dyslipidemia, where especially small, dense lipoprotein particles are atherogenic. The glucagon-like peptide-1 receptor agon
Autor:
Kshitij A. Desai, Sangeeta Adak, Mohamed A. Zayed, Malik Darwech, Gayan S. De Silva, Nikolai Harroun, Luis A. Sanchez, Uzma Naim, Clay F. Semenkovich, Xiaohua Jin
Publikováno v:
Atherosclerosis
BACKGROUND AND AIMS: Diabetes is an independent risk factor for carotid artery stenosis (CAS). Fatty acid synthase (FAS), an essential de novo lipogenesis enzyme, has increased activity in the setting of diabetes that leads to altered lipid metabolis