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Autor:
Xia Meng, Hao Li, Jinxi Lin, Yilong Wang, Yongjun Wang, Anxin Wang, Nan Zhang, Guojuan Chen, Liye Dai, Yingting Zuo
Publikováno v:
Atherosclerosis. 297:74-80
Low-density lipoprotein (LDL) and oxidized low-density lipoprotein (oxLDL) levels are thought to be related to recurrent stroke. However, the joint association of circulating LDL and oxLDL levels with the outcomes of acute minor ischemic stroke and t
Autor:
Parveen K. Garg, Steven Shea, Matthew A. Allison, James H. Stein, Laurent Yvan-Chavret, Robyn L. McClelland, Neal W. Jorgensen, Alan R. Tall
Publikováno v:
Atherosclerosis
Background and aims We aimed to assess the relationship of HDL (high-density lipoprotein)-mediated cholesterol mass efflux capacity (CMEC) with risk of incident peripheral artery disease (PAD). Methods CMEC was measured in 1458 Multi-Ethnic Study of
Autor:
Vito Di Marco, Vincenza Calvaruso, Salvatore Petta, Mariarosaria Saturnino, Riccardo Nevola, Pia Clara Pafundi, Ferdinando Carlo Sasso, Carmine Coppola, Graziano Troina, Aldo Marrone, Francesca Rini, Laura Staiano, Anna Ludovica Fracanzani, Barbara Guerrera, Mauro Giordano, Luigi Elio Adinolfi, Vincenzo Narciso, Rosa Lombardi, Luca Rinaldi, Antonio Craxì, Antonio Solano
Publikováno v:
Atherosclerosis. 296:40-47
Background and aims: HCV is associated with an increased risk of cardiovascular events (CV). Whether HCV clearance by direct-acting antivirals (DAA) reduces incident CV disease is poorly understood. We investigate whether HCV eradication reduces CV e
Autor:
Manal Zabalawi, Russel C. Sequeira, Yan Nie, Xuewei Zhu, Elena Boudyguina, Tiantong Ou, Jennifer H. Madenspacher, Qingxia Zhao, Zhan Wang, Jonathan M. Nelson, Michael B. Fessler
Publikováno v:
Atherosclerosis
Background and aims Dietary long-chain (≥20 carbons) n-3 polyunsaturated fatty acids (PUFAs) reduce atherosclerosis and enhance macrophage autophagy activation. How macrophage autophagy impacts atherosclerotic progression, particularly when compari
Autor:
Julia Dittrich, Christin Helmschrodt, Susen Becker, Holger Staab, Jenny Leopold, Gabriela Aust, Olaf Richter, Uta Ceglarek, Silvio Rohm
Publikováno v:
Atherosclerosis. 295:18-24
Background and aims Circulating sterols result either from cholesterol (CH) synthesis or intestinal uptake. They are mainly esterified and can be oxygenated. Sterols accumulate in atherosclerotic plaques whereby their clinical impact is uncertain. He
Autor:
Heval M. Kelli, Vasanth Sathiyakumar, Roger S. Blumenthal, Anurag Mehta, Wesley T. O'Neal, Laurence S. Sperling, Pratik B. Sandesara, Seth S. Martin, Michael J. Blaha
Publikováno v:
Atherosclerosis. 292:224-229
Individuals with low-density lipoprotein cholesterol (LDL-C) ≥190 mg/dL are considered high-risk and current guidelines recommend initiating high-intensity statin therapy in this group. We sought to examine the predictive ability of zero CAC in thi
Autor:
Lior Charach, Gideon Charach, Itamar Grosskopf, Shely Vons, Ilya Novikov, Leonid Galin, Eli Karniel
Publikováno v:
Atherosclerosis. 293:79-85
Hypercholesterolemia is a major risk factor for atherosclerosis, which is a cornerstone of coronary artery disease (CAD), stroke, peripheral vascular disease, aortic aneurysm and renal artery stenosis. This study investigated the association of bile
Autor:
Kai Kappert, Henryk Dreger, Benjamin Blaschke, Raphaela Fritsche-Guenther, Karl Stangl, Patrizia Brunner, Cornelia Bartsch, Andreas Benn, Yoann Gloaguen, Frederike Kramer, Jennifer A. Kirwan, Eric Witt, Elke Hammer, Angelika Vietzke, Verena Stangl, Petra Knaus, Hoang Giang Nguyen, Mario Lorenz
Publikováno v:
Atherosclerosis. 291:99-106
Background and aims Gonadal hormones are mainly thought to account for sex and gender differences in the incidence, clinical manifestation and therapy of many cardiovascular diseases. However, intrinsic sex differences at the cellular level are mostl
Publikováno v:
Atherosclerosis. 290:19-30
Background and aims Aberrant fucosylation, such as α-1,6 fucosylation catalyzed by fucosyltransferase 8 (Fut8), is associated with reduced cell migration and is responsible for cholesterol-enriched foam cell accumulation in the intima in the early s
Publikováno v:
Atherosclerosis. 288:101-111
Background and aims Atherosclerosis is usually the underlying cause of heart attacks, strokes and peripheral vascular diseases – collectively known as cardiovascular diseases. Oxidation of low density lipoprotein (LDL) and its lipid content has an