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Autor:
Ronny Baber, Kerstin Wirkner, Petra Büttner, Joachim Thiery, Holger Thiele, Christoph Engel, Uta Ceglarek, Clemens Ringel, Paul Schellong, Julia Dittrich, Markus Löffler, Carl Beuchel, Markus Scholz, Alexander Gaudl, Andrej Teren, Frank Beutner
Publikováno v:
Atherosclerosis. 335:62-67
The association of plasma trimethylamine N-oxide (TMAO) with atherosclerotic cardiovascular disease (ASCVD), diabetes mellitus (DM) and its determinants, as well as the role of TMAO as a predictor for short and long-term mortality, is still under dis
Publikováno v:
Atherosclerosis. 333:75-82
Phenylacetylglutamine (PAG), a gut microbiota metabolite, has recently been found to be associated with major adverse cardiovascular events. In this study, we analyzed the relationship between plasma PAG and coronary atherosclerotic severity assessed
Autor:
Meian He, Rong Peng, Chun Zhang, Lue Zhou, Rundong Niu, Xiaomin Zhang, Hui Gao, Wending Li, Yu Yuan, Tangchun Wu, Yang Xiao, Handong Yang, Kang Liu
Publikováno v:
Atherosclerosis. 333:1-8
Background and aims It remains unclear whether extreme levels of blood urea nitrogen (BUN) and BUN to creatinine ratio (BUN/Cr) can increase future risk of stroke. We conducted this study to investigate the associations of BUN and BUN/Cr with inciden
Publikováno v:
Atherosclerosis. 330:29-35
The association of triglyceride-rich lipoprotein-cholesterol (TRL-C) with recurrent cardiovascular events (RCVEs) has not been studied. Moreover, whether inflammation can affect TRL-C-associated cardiovascular risk is unknown. This study sought to ex
Autor:
Josefa Girona, Ana-Irene Malo, Núria Amigó, Núria Plana, Daiana Ibarretxe, Cèlia Rodríguez-Borjabad, Lluís Masana
Publikováno v:
Atherosclerosis. 330:1-7
Background and aims Inflammation is a pathophysiological mechanism of atherosclerosis, and several mediators have been proposed as biomarkers. Acute-phase serum glycoproteins are upregulated in the liver during systemic inflammation. Because of their
Autor:
Arthur Mader, Heinz Drexel, Berthold Moser, Alexander Vonbank, Daniela Zanolin-Purin, Barbara Larcher, Christoph H. Saely, Christine Heinzle
Publikováno v:
Atherosclerosis. 329:44-49
Background and aims The low density lipoprotein cholesterol to Apolipoprotein B (LDL-C/ApoB) ratio is a validated proxy for low density lipoprotein (LDL) particle size that can be easily calculated from a standard lipid/apolipoprotein profile. Whethe
Autor:
Kotb Abbass Metwalley, Magda Farghali Gabri, Hekma Saad Farghaly, Duaa M. Raafat, Magdy Algowhary, Ghada Mohamed Saied
Publikováno v:
Atherosclerosis. 328:38-43
Patients with congenital adrenal hyperplasia (CAH) are at increased risk of cardiometabolic abnormalities. We aimed to evaluate vascular endothelial dysfunction and its association with serum neopterin (NP) levels in CAH patients.The study included 4
Autor:
Shoichiro Izawa, Yuichiro Yano, Mitsuhide Naruse, Yoshiro Chiba, Tatsuya Kai, Kouichi Tamura, Norio Wada, Nobuhito Hirawa, Shintaro Okamura, Kenji Oki, Akiyo Tanabe, Takamasa Ichijo, Isao Kurihara, Nobuya Inagaki, Mika Tsuiki, Masanobu Yamada, Takuyuki Katabami, Koichi Yamamoto, Hiroki Kobayashi, Tatsuya Haze
Publikováno v:
Atherosclerosis. 324:84-90
Background and aims We used a dataset from a Japanese nationwide registry of patients with primary aldosteronism, to determine which of the parameters of hyperaldosteronism and blood pressure before or after treatments for primary aldosteronism (i.e.
Autor:
Ana M. Bea, Jacinto Fernández-Pardo, Itziar Lamiquiz-Moneo, Estíbaliz Jarauta, Victoria Marco-Benedí, C. López-Ariño, Rocío Mateo-Gallego, Fernando Civeira, Ana Cenarro, Lia Ferraro
Publikováno v:
Atherosclerosis. 315:24-32
Background and aims Glycerol kinase deficiency (GKD) is a rare genetic disorder characterized by hyperglycerolemia and glyceroluria, which could be misdiagnosed as a moderate to severe hypertriglyceridemia (HTG). We aimed to describe four novel cases
Autor:
Yi Zhang, Robert Pordy, Alberico L. Catapano, Vladimir Son, Evelyn Gasparino, Shazia Ali, Daniel A. Gipe, Mariko Harada-Shiba
Publikováno v:
Atherosclerosis. 314:33-40
Evinacumab, an angiopoietin-like protein 3 monoclonal antibody, reduced low-density lipoprotein cholesterol (LDL-C) significantly in a Phase 2 study of patients with homozygous familial hypercholesterolemia. In this double-blind, placebo-controlled P