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Publikováno v:
Atherosclerosis. 253:22-28
Background and aims Sclerostin and Dickkopf-1 (Dkk-1) are potent antagonists of Wnt signalling and might therefore play important roles in cardiovascular disease. We investigated whether serum sclerostin and Dkk-1 levels are associated with acute isc
Autor:
Jeremy Yuvaraj, Andrew Lin, James C.G. Doery, Ravi Kiran Munnur, S. Mirzaee, Stephen J. Nicholls, R. Modi, Nitesh Nerlekar, Ashray Rajagopalan, Sujith Seneviratne, Dennis T.L. Wong, Michelle Seckington
Publikováno v:
Atherosclerosis. 284
There remains a substantial residual risk of ischaemic heart disease (IHD) despite optimal low-density lipoprotein cholesterol (LDLC) reduction. Part of this risk may be attributable to remnant cholesterol, which is carried in triglyceride-rich lipop
Autor:
Yonghong Zhang, Jing Chen, Tian Xu, Xiaoqing Bu, Chongke Zhong, Deqin Geng, Zhengbao Zhu, Hao Peng, Jiang He, Tan Xu, Xiaowei Zheng, Zhong Ju, Aili Wang, Yanbo Peng, Daoxia Guo, Qunwei Li
Publikováno v:
Atherosclerosis. 285
The association between homocysteine and prognosis of ischemic stroke remains controversial, and the role of platelet count on the effects of homocysteine in the prognosis of ischemic stroke is still not elucidated.A total of 3229 acute ischemic stro
Autor:
Mehmet Sertac Alpaydin, Kadri Murat Gurses, Sukru Karaarslan, Zafer Buyukterzi, Meral Buyukterzi, Mehmet Mustu
Publikováno v:
Atherosclerosis. 315:e62
Aortic sclerosis is associated with increased cardiovascular mortality and morbidity. Numerous studies have shown that visceral adiposity is associated with development of atherosclerosis, especially in the adjacent vascular wall. Considering the sim
Publikováno v:
Atherosclerosis. 251:454-459
Background and aims Previous results of the AIM-HIGH trial showed that baseline levels of the conventional lipid parameters were not predictive of future cardiovascular (CV) outcomes. The aims of this secondary analysis were to examine the levels of
Autor:
Thierry Aubry, Karine Pichavant-Rafini, Jean-Claude Desfontis, Michael Theron, Emmanuelle Plee-Gautier, Romain Didier, Florine Tissier, Yassine Mallem, Christelle Goanvec, Nathalie Bourgeois, Yann Le Grand, Philippe Roquefort, Jacques Mansourati, Matthieu Dubreuil, Martine Gilard
Publikováno v:
Atherosclerosis. 251:70-77
Background and aims Statins are prescribed for their preventative effects within atherosclerosis development. To our knowledge, no study focusing on very low-dose (non-hypolipidemic effect) and long-term atorvastatin treatment in vivo was available.
Autor:
Dongliang Wang, Ding Ding, Chaoqun Liu, Wenhua Ling, Yunou Yang, Qing Li, Xinrui Li, Yuan Zhang, Yuanzhu Zheng
Publikováno v:
Atherosclerosis. 249:116-124
Although diminished cholesterol efflux capacity is positively related with prevalent coronary artery disease, its prognostic value for incident cardiovascular events remains a topic of debate. This work aims to investigate the association between cho
Autor:
Jin M. Cheng, Patrick W. Serruys, Eric Boersma, Hector M. Garcia-Garcia, K. Martijn Akkerhuis, Isabella Kardys, Robert-Jan van Geuns, Rohit M. Oemrawsingh
Publikováno v:
Atherosclerosis, 248, 117-122. Elsevier Ireland Ltd
Background and aims Experimental studies have suggested that proprotein convertase substilisin/kexin type 9 (PCSK9) might directly promote inflammatory processes contributing to atherosclerosis by mechanisms independent of low-density lipoprotein (LD
Autor:
Jingbo Hou, Nana Dong, Shengliang Liu, Xuefeng Ren, Jiannan Dai, Lijia Ma, Jinwei Tian, Bo Yu, Lei Xing, Huai Yu
Publikováno v:
Atherosclerosis. 247:111-117
Cholesterol Crystals (ChCs) are recognized as a hallmark of advanced atherosclerotic lesions. Previous animal and histopathology studies have revealed that Cholesterol crystallization trigger a local inflammatory response and plaque rupture. We sough
Publikováno v:
Atherosclerosis. 246:63-70
Background and aims Triglyceride-rich lipoproteins are causally associated with high risk of ischemic heart disease (IHD), and apolipoprotein E (apoE) has a central role in their plasma clearance. While both quantitative and qualitative changes of ap