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Autor:
Qingyi Zhu, Yichao Xiao, Meng Jiang, Xuanyou Liu, Yuqi Cui, Hong Hao, Gregory C. Flaker, Qiming Liu, Shenghua Zhou, Zhenguo Liu
Publikováno v:
Atherosclerosis. 357:41-50
Inflammation and reactive oxygen species (ROS) are important to the pathogenesis of atherosclerosis. The effect of antioxidants on atherosclerosis is inconsistent, and sometimes controversial. We aimed to test the hypothesis that attenuation of ather
Autor:
Omar Dzaye, Alexander C. Razavi, Erin D. Michos, Martin Bødtker Mortensen, Zeina A. Dardari, Khurram Nasir, Albert D. Osei, Allison W. Peng, Ron Blankstein, John H. Page, Michael J. Blaha
Publikováno v:
Dzaye, O, Razavi, A C, Michos, E D, Mortensen, M B, Dardari, Z A, Nasir, K, Osei, A D, Peng, A W, Blankstein, R, Page, J H & Blaha, M J 2022, ' Coronary artery calcium scores indicating secondary prevention level risk : Findings from the CAC consortium and FOURIER trial ', Atherosclerosis, vol. 347, pp. 70-76 . https://doi.org/10.1016/j.atherosclerosis.2022.02.006
BACKGROUND AND AIMS: Coronary artery calcium (CAC) burden displays a stepwise association with atherosclerotic cardiovascular disease (ASCVD) risk. Among primary prevention patients, we sought to determine the CAC scores equivalent to ASCVD mortality
Autor:
Steven P. Grover, Taylor Coughlin, Salma M. Fleifil, Jens J.N. Posma, Henri H.M. Spronk, Stefan Heitmeier, A. Phillip Owens, Nigel Mackman
Publikováno v:
Atherosclerosis, 345, 7-14. Elsevier Ireland Ltd
BACKGROUND AND AIMS: The platelet inhibitor aspirin reduces inflammation and atherosclerosis in both apolipoprotein E deficient (apoE-/-) mice and low-density lipoprotein receptor deficient (Ldlr-/-) mice. Similarly, the factor Xa inhibitor rivaroxab
Autor:
Seung-Jae Lee, Hyunah Kim, Byeong Kil Oh, Hyo-In Choi, Jong Young Lee, Sung Ho Lee, Byung Jin Kim, Bum Soo Kim, Jin Ho Kang, Jeonggyu Kang, Seong Hwan Kim, Ki-Chul Sung
Publikováno v:
Atherosclerosis. 342:19-24
Inter-arm blood pressure differences (IADs) are known to be associated with adverse cardiovascular outcomes. We evaluated the distribution of IADs in a large cohort of apparently healthy people and the association of IADs with brachial-ankle pulse wa
Autor:
Ty Sweeney, Chiadi E Ndumele, Oluwaseun E. Fashanu, Bhavya Varma, Matthew A. Allison, Apurva Sharma, Matthew J. Budoff, Erin D. Michos, Alain G. Bertoni, Oluseye Ogunmoroti, Di Zhao
Publikováno v:
Atherosclerosis
Background and aims Extra-coronary calcification (ECC) is a marker of atherosclerosis and independently associated with cardiovascular disease (CVD). Adipokines may mediate the effect of obesity on atherosclerosis. However, the relationship of adipok
Publikováno v:
Atherosclerosis. 328:23-32
Background and aims The thiol transferase glutaredoxin 1 controls redox signaling and cellular functions by regulating the S-glutathionylation status of critical protein thiols. Here we tested the hypothesis that by derepressing the expression of glu
Autor:
Aaron R. Folsom, Caitlin W. Hicks, Josef Coresh, Shoshana H. Ballew, Gerardo Heiss, Kunihiro Matsushita, Elizabeth Selvin, James H. Black, Corey A. Kalbaugh, Ning Ding, Lucia Kwak
Publikováno v:
Atherosclerosis
BACKGROUND AND AIMS: Previous community-based studies have demonstrated sex and race-based disparities in the risk of cardiovascular disease. We sought to examine the association of sex and race with incident peripheral artery disease (PAD) and criti
Autor:
Ellen Boakye, Zeina Dardari, Olufunmilayo H. Obisesan, Albert D. Osei, Frances M. Wang, Yasuyuki Honda, Omar Dzaye, Ngozi Osuji, John Jeffery Carr, Candace M. Howard-Claudio, Lynne Wagenknecht, Suma Konety, Josef Coresh, Kunihiro Matsushita, Michael J. Blaha, Seamus P. Whelton
Publikováno v:
Atherosclerosis. 355
The prevalence of aortic valve calcification (AVC) increases with age. However, the sex-and race-specific burden of AVC and associated cardiovascular risk factors among adults ≥75 years are not well studied.We calculated the sex-and race-specific b
Autor:
Michael Blaha, Matthew J. Budoff, Namratha R. Kandula, Salim S. Virani, Michael H. Criqui, Mahmoud Al Rifai, Alka M. Kanaya, Miguel Cainzos-Achirica, Jaideep Patel
Publikováno v:
Atherosclerosis
Background and aims South Asians (SA) experience disproportionately higher rates of atherosclerotic cardiovascular disease (ASCVD) events than non-Hispanic whites (NHW) and several other Asian groups. The coronary artery calcium (CAC) Agatston score
Autor:
Barbara Dietel, Miyuki Tauchi, Gerhard Krönke, Fabian Seibert, Christoph J. Binder, Jochen A. Ackermann, Maria Oszvar-Kozma, Katharina Hofheinz, Hartmut Kühn, Georg Schett
Publikováno v:
Atherosclerosis. 311:67-72
Background and aims Oxidation of low-density lipoprotein (LDL) and oxidized LDL-mediated activation of the innate immune system have been recognized as early key events during the pathogenesis of atherosclerosis. Recent evidence identified eosinophil