Zobrazeno 1 - 10
of 312
pro vyhledávání: ''
Autor:
Isabelle Ruel, Zubin Lahijanian, Daniel Gaudet, Alexandre M. Bélanger, Jacques Genest, Jean Bergeron, Alexis Baass, Etienne Khoury, Latifah Alothman, Diane Brisson, Patrick Couture, Sumayah Aljenedil, Leslie Brown
Publikováno v:
Atherosclerosis. 310:54-63
Background and aims Homozygous familial hypercholesterolemia (HoFH) is an orphan disease, most often caused by bi-allelic mutations of the LDLR gene. Patients with HoFH have elevated LDL-C levels >13 mmol/L, tendinous xanthomata and severe, premature
Autor:
Jean Bergeron, Patrick Couture, Benoît Lamarche, André J. Tremblay, Jean-Philippe Drouin-Chartier
Publikováno v:
Atherosclerosis. 270:26-32
Background and aims Maximizing the acute reduction of LDL-cholesterol (C) and lipoprotein (a) (Lp(a)) concentrations in patients with homozygous familial hypercholesterolemia (HoFH) is the main goal of lipoprotein apheresis (LA). The objective of thi
Autor:
Brian R. Weil, Christopher A. DeSouza, Jared J. Greiner, Brian L. Stauffer, Anthony R. Bain, Kyle J. Diehl
Publikováno v:
Atherosclerosis. 265:41-46
Habitual short nightly sleep duration is associated with increased atherosclerotic cardiovascular disease risk and morbidity. Vascular endothelial dysfunction represents an important mechanism that may underlie this heightened cardiovascular risk. Im
Autor:
Juan P Valderas, Patricia Hidalgo, Susana Contreras, César González, Olga Panes, Diego Mezzano, Jaime Pereira, Mónica Acevedo, Ximena Sánchez, Attilio Rigotti
Publikováno v:
Atherosclerosis. 257:164-171
Background and aims High plasma LDL-cholesterol (LDL-C) and platelet responses have major pathogenic roles in atherothrombosis. Thus, statins and anti-platelet drugs constitute mainstays in cardiovascular prevention/treatment. However, the role of pl
Autor:
Oscar Pérez-Méndez, Carolane Dauteuille, Alejandro Zentella-Dehesa, Philippe Lesnik, Carlos A Aguilar Salinas, Sharim Saucedo, Francisco Lozano-Arvizu, Griselda X Brito-Córdova, Anatol Kontush, M. John Chapman, Marie Lhomme, Raúl Julián Ortiz-Bautista, Liliana Muñoz-Hernandez
Publikováno v:
Atherosclerosis. 277
Background and aims Research on the biologic activities of HDL, such as cholesterol efflux capacity and HDL composition, has allowed the understanding of the effect of interventions directed to improve cardiovascular risk. Previously, statin therapy
Autor:
Thomas Dembinski, Gerald Salen, Barbara Triggs-Raine, David Mymin, Grant M. Hatch, Darrell J. Waggoner
Publikováno v:
Atherosclerosis. 269
Background and aims Phytosterolemia is a rare genetic disease caused by mutation of the ABCG5/8 gene. Our aim was to elucidate the natural history and homeostasis of phytosterolemia. Methods We analyzed a Hutterite kindred consisting of 21 homozygote
Autor:
Xavier Palomer, Juan F. Ascaso, Sergio Martínez-Hervás, Manuel Vázquez-Carrera, Núria Plana, Josep Julve, Luis Masana, Josefa Girona, Anna Cabré, Mercedes Heras, Francisco Blanco-Vaca, Xavier Correig, Helena Quesada, Núria Amigó, José T. Real
Publikováno v:
Atherosclerosis. 238:213-219
HDL-increasing drugs such as fenofibrate and niacin have failed to decrease the cardiovascular risk in patients with type 2 diabetes. Drug-mediated quantitative and qualitative HDL modifications could be involved in these negative results. To evaluat
Autor:
Chiara Bellacosa, Renato Maserati, Rosaria Viglietti, Antonio Chirianni, Elena Ricci, Stefania Cicalini, Paolo Maggi, Paola Corsi, Canio Martinelli, Gioacchino Angarano, Nicoletta Ladisa, Anna Volpe, Elisabetta Grilli, Armando Leone, Federica Sozio, Benedetto Maurizio Celesia, Lara Ines Bellazzi
Publikováno v:
Atherosclerosis. 263
Background and aims PREVALEAT (PREmature VAscular LEsions and Antiretroviral Therapy) II is a multicenter, longitudinal cohort study aimed at the evaluation of cardiovascular risk among advanced HIV-positive, treatment-naive patients starting their f
Autor:
Robert D. Steiner, Peter B. Jones, David Mymin, Semone B. Myrie, Jean Baptiste Roullet, Rgia A. Othman
Publikováno v:
Atherosclerosis. 260
Sitosterolemia displays high plasma total sterols [high plant sterols (PS) + normal to high total cholesterol (TC)] with normal to moderately elevated low-density lipoprotein (LDL) levels. High LDL, intermediate-density lipoprotein (IDL) and very low
Autor:
Joseph L. Witztum, Yohan Bossé, Patrick Mathieu, Sotirios Tsimikas, Romain Capoulade, Jean-Pierre Després, Jean G. Dumesnil, Philippe Pibarot, James W. Tam, Xiaohong Yang, Koon K. Teo, Kwan L. Chan, Benoit J. Arsenault
Publikováno v:
Atherosclerosis. 260
Background and aims Elevated levels of lipoprotein(a) [Lp(a)] and oxidized phospholipids on apolipoprotein B-100 (OxPL-apoB) predict the progression of pre-existing mild-to-moderate calcific aortic valve stenosis (CAVS). Whether indirect markers of o