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Autor:
Ghasem Mosayebi, Mahdieh Mondanizadeh, Malihe Bagheri, Behzad Khansarinejad, Alireza Moradabadi
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Chronic lymphocytic leukemia (CLL) is one of the most common hematologic malignancy in adults worldwide. This cancer has a poor prognosis at different stages. So, the identification of new biomarkers is important for diagnosis of B-CLL. C
Autor:
Gamal Osman, Ahmed M. Elsayed, Walid S.H. Elsayed, Ola A. Harb, Adel Mahmoud Morsy, Ahmed A. Obaya, Amrallah A. Mohammed, Ahmed S Allam, Hanaa Rashied
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Despite the significant progress in target therapy for the treatment of metastatic colorectal carcinoma (mCRC), the overall survival isn’t satisfactory. Methods: We assessed the expression of Amphiregulin, PTEN, and P21 in sections from
Prognostic Significance of Tripartite Motif Containing 16 Expression in Patients with Gastric Cancer
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background and Aim: Tripartite Motif Containing 16 (TRIM16) is a member of the TRIM protein family which is known to play a suppressor role in development of numerous tumor types. However, a positive correlation between TRIM16 expression and gastric
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Objective Chronic Lymphocytic Leukemia (CLL) is a common leukemia among Caucasians but rare in Asians population. We postulated that aberrant methylation either hypermethylation or partial methylation might be one of the silencing mechanisms that ina
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: The data about the clinical impact of NOTCH1 mutations among Egyptians B – cell chronic lymphocytic patients is not previously identified. We herein, evaluate the prevalence and the prognostic significance of neurogenic locus notch homo
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Introduction Breast cancer (BC) is the most common malignancy affecting females worldwide. Various risk factors play a role in the developing of BC. Infectious agents like viruses have been proposed for this cancer and Epstein-Barr virus (EBV) is a w
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: The phosphatidylinositol-3 kinase (PI3K) intracellular signaling pathway plays an important role in breast cancer. The current study aimed to evaluate the expressions of two main regulators of PI3K pathway; phosphatidylinositol-3- kinase
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: The use of targeted specific genes in therapeutic and treatment decisions has been considered for lung cancer. The epidermal growth factor receptor (EGFR) gene, which is over expressed in non-small cell lung cancer (NSCLC), was considered
Autor:
Saravana Kumar Velusamy, Ramya S Vokuda, Venkastesh S Madhugiri, Surendra Kumar Verma, Srinivas B H
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Leptin, an adipocytokine functions via the leptin receptor, OB-Rb that contains an intact intracellular domain and activates the JAK/STAT signalling cascade. It stimulates growth, migration and invasion of cancer cells in vitro potentiati
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Timely and sensitive diagnosis of gastric cancer is crucial for efficient treatment and survival of the patients. microRNAs have been considered as diagnostic biomarkers in different type of cancers including gastric cancer. In the presen