Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alan R. Shuldiner"'
Autor:
Braxton D. Mitchell, Michael L. Terrin, Nanette I. Steinle, Richard B. Horenstein, Alan R. Shuldiner, Kathleen A. Ryan, Klaus von Bergmann, Dieter Lütjohann, Wendy S. Post
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:413-419
Objective— To determine whether long-term exposure to moderate elevations in plasma plant sterol levels increases risk for atherosclerosis. Methods and Results— In Old Order Amish participants aged 18 to 85 years, with (n=110) and without (n=181)
Autor:
Michael Pacanowski, Joshua D. Backman, Richard B. Horenstein, Joshua P. Lewis, Jeffrey R. O'Connell, Laura M. Yerges-Armstrong, William D. Figg, Alan R. Shuldiner
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Clopidogrel with aspirin is standard of care for the secondary prevention of ischemic events in patients with acute coronary syndromes. However, substantial inter-individual variation in clopidogrel response results in sub-optimal therapy in some pat
Autor:
Jeffery R. O'Connell, Nehal N. Mehta, Xuexia Wang, Elizabeth A. Streeten, Laura M. Yerges-Armstrong, Sharon L.R. Kardia, Braxton D. Mitchell, Jane F. Ferguson, Min A. Jhun, Mingyao Li, Jie Liu, Hakan Hakonarson, Brendan J. Keating, Alan R. Shuldiner, Lawrence F. Bielak, Patricia A. Peyser, Yan V. Sun, James E. Hixson, Daniel J. Rader, Muredach P. Reilly, Haiqing Shen, Daniel L. Koller, Wendy S. Post
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 30:2648-2654
Objective— The vitamin D endocrine system is essential for calcium homeostasis, and low levels of vitamin D metabolites have been associated with cardiovascular disease risk. We hypothesized that DNA sequence variation in genes regulating vitamin D
Autor:
Jeffrey R. O'Connell, Braxton D. Mitchell, Toni I. Pollin, Ikhide G. Imumorin, Alan R. Shuldiner, Wen-Chi Hsueh, Rasa Kazlauskaite, Nanette I. Steinle
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 24:1708-1713
Objective— Metabolic syndrome is associated with increased risk for cardiovascular disease and type 2 diabetes mellitus (T2DM). The lamin A/C ( LMNA ) gene, mutations of which cause rare syndromes of severe insulin resistance and dyslipidemia, is l