Zobrazeno 1 - 10
of 69
pro vyhledávání: ''
Autor:
Annika Rosengren, Jari Martikainen, Ola Hjelmgren, Göran Bergström, Claes Ohlsson, Maria Bygdell, Jenny M. Kindblom
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41:2318-2327
Objective: The aim with the present study was to evaluate the association between pubertal body mass index (BMI) change and adult coronary artery calcification (CAC) score and risk of acute coronary events. Approach and Results: We included 37 672 me
Autor:
Michael G. Levin, Neil M Davies, Julie Lynch, Pradeep Natarajan, Todd L. Edwards, Philip S. Tsao, Daniel J. Rader, Dipender Gill, Benjamin F. Voight, Kyung Min Lee, Derek Klarin, Kyong-Mi Chang, Venexia M Walker, Scott M. Damrauer, Themistocles L. Assimes, Jacklyn N. Hellwege, J. Michael Gaziano, Adriana M. Hung, Jacob M. Keaton
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: We aimed to estimate the effect of blood pressure (BP) traits and BP-lowering medications (via genetic proxies) on peripheral artery disease. Approach and Results: Genome-wide association studies summary statistics were obtained for BP, pe
Autor:
Francisco Lopez-Jimenez, Jeffrey W. Meeusen, Manlio Vinciguerra, Allan S. Jaffe, Richard R. Rodeheffer, Jose R. Medina Inojosa, Vlad C. Vasile, Christopher G. Scott, Leslie J. Donato, Meredith Hyun
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective:Cardiovascular disease remains a leading cause of mortality worldwide. Ceramide scores have been associated with adverse outcomes in patients with established coronary artery disease. The prognostic value of ceramide score has not been asse
Autor:
Kevin P. Bliden, Paul A. Gurbel, Lidija Covic, Athan Kuliopulos, Elizabeth K. Fletcher, Susan E. Turner, Jeffrey J. Rade, Daniel H. Cox, Carey Kimmelstiel
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Arterial thrombosis leading to ischemic injury worsens the prognosis of many patients with cardiovascular disease. PZ-128 is a first-in-class pepducin that reversibly inhibits PAR
Objective: Arterial thrombosis leading to ischemic injury worsens the prognosis of many patients with cardiovascular disease. PZ-128 is a first-in-class pepducin that reversibly inhibits PAR
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:1982-1989
Atherosclerosis is a systemic disease that involves multiple vascular beds. The pathological characteristics and clinical presentation, however, vary among the different vascular territories. Acute coronary syndrome is a relatively common manifestati
Autor:
Laura M. Lyall, Joey Ward, Rona J. Strawbridge, Daniel J. Smith, Richard J. Shaw, Breda Cullen, Amy Ferguson, Mark E.S. Bailey, Nicholas Graham, Rachana Tank, Robert Pearsall, Jill P. Pell, Donald M. Lyall, Keira J.A. Johnston
Publikováno v:
Arterioscler Thromb Vasc Biol
Strawbridge, R J, Ward, J, Bailey, M E S, Cullen, B, Ferguson, A, Graham, N, Johnston, K J A, Lyall, L M, Pearsall, R, Pell, J, Shaw, R J, Tank, R, Lyall, D M & Smith, D J 2019, ' Carotid intima-media thickness novel loci, sex-specific effects, and genetic correlations with obesity and glucometabolic traits in UK Biobank ', Arteriosclerosis, Thrombosis, and Vascular Biology, pp. 446-461 . https://doi.org/10.1161/ATVBAHA.119.313226
Strawbridge, R J, Ward, J, Bailey, M E S, Cullen, B, Ferguson, A, Graham, N, Johnston, K J A, Lyall, L M, Pearsall, R, Pell, J, Shaw, R J, Tank, R, Lyall, D M & Smith, D J 2019, ' Carotid intima-media thickness novel loci, sex-specific effects, and genetic correlations with obesity and glucometabolic traits in UK Biobank ', Arteriosclerosis, Thrombosis, and Vascular Biology, pp. 446-461 . https://doi.org/10.1161/ATVBAHA.119.313226
Objective: Atherosclerosis is the underlying cause of most cardiovascular disease, but mechanisms underlying atherosclerosis are incompletely understood. Ultrasound measurement of the carotid intima-media thickness (cIMT) can be used to measure vascu
Autor:
Seung Yul Lee, Seung-Jung Park, Yangsoo Jang, Chul Min Ahn, Jung-Min Ahn, Donghoon Choi, Jung Sun Kim, Byeong Keuk Kim, Duk-Woo Park, Myeong Ki Hong, Gary S. Mintz, Sung Jin Hong, Young Guk Ko
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:288-295
Objective: The goal of this study was to determine the impact of late-acquired stent malapposition (LASM) on long-term clinical outcomes in patients treated with coronary stent implantation. Approach and Results: We investigated major adverse cardiac
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 39:2207-2219
Unstable coronary plaques that are prone to erosion and rupture are the major cause of acute coronary syndromes. Our expanding understanding of the biological mechanisms of coronary atherosclerosis and rapid technological advances in the field of med
Autor:
Martin O Schmiady, Thomas F. Lüscher, Peter Libby, Giovanni G. Camici, Alexander Akhmedov, Michael Reinehr, Simon Kraler, Paul C. Evans
Publikováno v:
Arterioscler Thromb Vasc Biol
Fueled by the global surge in aging, atherosclerotic cardiovascular disease reached pandemic dimensions putting affected individuals at enhanced risk of myocardial infarction, stroke, and premature death. Atherosclerosis is a systemic disease driven
Autor:
Yi-An Ko, Qi Meng, Syed Ahmad, Laurence S. Sperling, Anurag Mehta, Aditi Nayak, Ananya Hooda, Anil Varughese, Xiaona Li, Zakaria Almuwaqqat, Devinder S. Dhindsa, Ayman Alkhoder, Melroy D'Souza, Shabatun J. Islam, Iraj Hesaroieh, Arshed A. Quyyumi, Annie H. Ho, Shivang R. Desai, Edmund K. Waller, Ali Mokhtari
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: The underlying pathobiology of the paradoxical relationship between obesity and adverse outcomes in coronary artery disease (CAD) is unclear. Our objective was to determine the as
Objective: The underlying pathobiology of the paradoxical relationship between obesity and adverse outcomes in coronary artery disease (CAD) is unclear. Our objective was to determine the as